Interactor 1: DSC2 (Q02487)
Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)
Gene: DSC2

Interactor 2: PKP2 (Q99959)
Plakophilin-2
Gene: PKP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 11790773
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~CADH_Y-type_LIR
Common GO terms GO:0001533 - cornified envelope
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0014704 - intercalated disc
GO:0030057 - desmosome
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 901
Hs

1 881
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024