HitPredict

Interactor 1: H11 (Q02539)
Histone H1.1 (Histone H1a)
Gene: H1-1

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16431907
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031490 - chromatin DNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 746
+	Mm
		990819 H1T_MOUSE (1-213): 1.33e-39: 136: 49.30		EZH2_MOUSE (1-746): 0: 860: 98.39
+	Hs
		559417 H13_HUMAN (1-169): 5.79e-27: 104: 55.03		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		559730 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		559109 H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		559470 H13_HUMAN (1-169): 5.79e-27: 104: 55.03		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Hs
		331717 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		331716 H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		559895 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Hs
		331706 H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		559217 H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Hs
		331791 H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		489205 H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Hs
		971335 H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00		NSD3_HUMAN (275-729): 9.41e-70: 251: 14.42
+	Hs
		489204 H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		971310 H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		559663 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54
+	Hs
		560010 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		SET1B_HUMAN (619-732): 1.38e-18: 93.2: 40.52
+	Hs
		489011 H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76		KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54
+	Hs
		971403 H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00		SET1B_HUMAN (619-732): 1.38e-18: 93.2: 40.52