Protein: RN186
E3 ubiquitin-protein ligase RNF186 (EC 2.3.2.27) (RING finger protein 186)

Gene: RN186, RNF186
Organism: Homo sapiens
Interactions: 13
UniProt ID: Q9NXI6

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0008270 - zinc ion binding
GO:0031625 - ubiquitin protein ligase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

971187

UBE2H
Ubiquitin-conjugating enzyme E2 H

2

1

Small-scale

0.619

High

710904

EPHB2
Ephrin type-B receptor 2

1

1

Small-scale

0.586

High

931820

EPHB3
Ephrin type-B receptor 3

1

1

Small-scale

0.535

High

982341

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

0

High-throughput

0.518

High

623573

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

Small-scale

0.513

High

1429864

TOLIP
Toll-interacting protein

1

0

Small-scale

0.513

High

1383350

Q96AL5
PBX3 protein

1

1

High-throughput

0.470

High

586347

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.460

High

1091992

SEC20
Vesicle transport protein SEC20

1

0

Small-scale

0.458

High

823983

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.439

High

944220

SCND1
SCAN domain-containing protein 1

2

0

High-throughput

0.316

High

390784

TFR1
Transferrin receptor protein 1

1

0

Small-scale

0.279

Low

945685

SESN2
Sestrin-2

1

0

Small-scale

0.261

Low


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Last updated: 11Aug2025