HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: CDK3 (Q00526)
Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)
Gene: CDK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36736316, 36931259
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 305
+	Hs
		667720 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		CDK2_HUMAN (1-292): 2.7e-149: 422: 76.71
+	Hs
		971411 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		CDK17_HUMAN (1-291): 1e-123: 365: 53.43
+	Hs
		897203 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		CDK7_HUMAN (3-296): 4.35e-124: 360: 45.64
+	Hs
		971410 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		CDK16_HUMAN (1-288): 4.22e-108: 324: 54.33
+	Sc
		602351 BMH1_YEAST (2-243): 2.44e-134: 381: 75.72		PHO85_YEAST (3-290): 1.25e-129: 372: 54.21