HitPredict

Interactor 1: FKBP4 (Q02790)
Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]
Gene: FKBP4

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	33545068, 14702098
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0030674 - protein-macromolecule adaptor activity and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 459 Hs			1 440
+	Hs
		684695 STIP1_HUMAN (259-458): 6.41e-12: 69.5: 11.51		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		972507 FKBP4_HUMAN (1-459): 1.71e-150: 437: 100.00		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Hs
		320043 AIPL1_HUMAN (141-421): 2.12e-50: 177: 18.34		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		118736 AIP_HUMAN (146-416): 1.8e-50: 176: 20.12		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Hs
		684721 STIP1_HUMAN (259-458): 6.41e-12: 69.5: 11.51		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78