HitPredict

Interactor 1: TFB2 (Q02939)
General transcription and DNA repair factor IIH subunit TFB2 (TFIIH subunit TFB2) (RNA polymerase II transcription factor B 52 kDa subunit) (RNA polymerase II transcription factor B p52 subunit) (RNA polymerase II transcription factor B subunit 2)
Gene: TFB2

Interactor 2: TFB4 (Q12004)
General transcription and DNA repair factor IIH subunit TFB4 (TFIIH subunit TFB4) (RNA polymerase II transcription factor B 34 kDa subunit) (RNA polymerase II transcription factor B p34 subunit) (RNA polymerase II transcription factor B subunit 4)
Gene: TFB4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.941

The method score is based on:

Property Details
Experiments 21876155, 26340423, 37968396, 14500720, 8657139, 15220919
Identification Methods pull down, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Tfb2~Tfb4
Common GO terms GO:0000112 - nucleotide-excision repair factor 3 complex
GO:0000439 - transcription factor TFIIH core complex
GO:0005675 - transcription factor TFIIH holo complex
GO:0006289 - nucleotide-excision repair
GO:0006366 - transcription by RNA polymerase II
and 1 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 513
Sc

1 338
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024