HitPredict

Interactor 1: PAX2 (Q02962)
Paired box protein Pax-2
Gene: PAX2

Interactor 2: PCGF5 (Q86SE9)
Polycomb group RING finger protein 5 (RING finger protein 159)
Gene: PCGF5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 256
+	Hs
		973875 PAX2_HUMAN (1-417): 2.32e-119: 355: 100.00		PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06
+	Hs
		641464 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		PCGF5_HUMAN (1-256): 3.16e-62: 197: 100.00
+	Hs
		620169 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		PCGF5_HUMAN (1-256): 3.16e-62: 197: 100.00
+	Hs
		641517 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		TRI11_HUMAN (3-254): 3.72e-48: 167: 13.77
+	Mm
		926113 PAX6_MOUSE (13-417): 4.77e-92: 285: 32.35		TRI11_MOUSE (3-254): 6.11e-46: 161: 13.41
+	Hs
		641552 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25
+	Hs
		641538 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		RING2_HUMAN (2-252): 1.71e-41: 146: 17.59
+	Hs
		641545 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06
+	Hs
		988776 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		PCGF5_HUMAN (1-256): 3.16e-62: 197: 100.00
+	Hs
		641384 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		RING1_HUMAN (2-142): 1.22e-34: 129: 20.42
+	Hs
		620193 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		RING2_HUMAN (2-252): 1.71e-41: 146: 17.59
+	Hs
		620197 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06
+	Hs
		878427 PAX9_HUMAN (13-246): 2.63e-54: 185: 45.11		PCGF5_HUMAN (1-256): 3.16e-62: 197: 100.00
+	Hs
		988798 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06
+	Hs
		971658 PAX5_HUMAN (1-417): 1.56e-97: 298: 62.20		LONF1_HUMAN (14-111): 2.86e-15: 76.8: 23.47
+	Hs
		641423 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		LONF1_HUMAN (14-111): 2.86e-15: 76.8: 23.47
+	Hs
		878459 PAX9_HUMAN (13-246): 2.63e-54: 185: 45.11		PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06
+	Hs
		988767 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		LONF1_HUMAN (14-111): 2.86e-15: 76.8: 23.47