Protein: GCFC2
Intron Large complex component GCFC2 (GC-rich sequence DNA-binding factor) (GC-rich sequence DNA-binding factor 2) (Transcription factor 9) (TCF-9)

Gene: GCFC2
Organism: Homo sapiens
Interactions: 60
UniProt ID: P16383

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594854

HDA11
Histone deacetylase 11

4

1

High-throughput

0.697

High

594857

DDX23
Probable ATP-dependent RNA helicase DDX23

4

1

High-throughput

0.694

High

289426

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

4

4

High-throughput

0.691

High

485561

RU2A
U2 small nuclear ribonucleoprotein A'

3

1

High-throughput

0.667

High

594826

CSK22
Casein kinase II subunit alpha'

3

1

High-throughput

0.667

High

594840

CSK21
Casein kinase II subunit alpha

3

1

High-throughput

0.667

High

594845

PRP8
Pre-mRNA-processing-splicing factor 8

3

2

High-throughput

0.667

High

594849

UBR2
E3 ubiquitin-protein ligase UBR2

4

0

High-throughput

0.661

High

594861

TFP11
Tuftelin-interacting protein 11

3

2

Small-scale

0.647

High

321428

PRP6
Pre-mRNA-processing factor 6

3

0

High-throughput

0.638

High

351310

SYF2
Pre-mRNA-splicing factor SYF2

2

1

High-throughput

0.628

High

594839

RUXE
Small nuclear ribonucleoprotein E

2

1

High-throughput

0.628

High

594865

PRP19
Pre-mRNA-processing factor 19

2

2

High-throughput

0.628

High

594831

BASI
Basigin

3

1

High-throughput

0.609

High

207434

DHX15
ATP-dependent RNA helicase DHX15

2

2

Small-scale

0.552

High

335774

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

1

High-throughput

0.536

High

574135

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

2

High-throughput

0.536

High

594864

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

1

High-throughput

0.536

High

594866

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

1

High-throughput

0.536

High

594837

ATX1
Ataxin-1

1

0

High-throughput

0.518

High

594848

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

0

High-throughput

0.518

High

250444

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

297923

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.513

High

484813

HXB7
Homeobox protein Hox-B7

1

0

High-throughput

0.513

High

569233

YJU2B
Probable splicing factor YJU2B

1

0

High-throughput

0.513

High

594829

GBP1
Guanylate-binding protein 1

1

0

High-throughput

0.513

High

594833

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

594835

CDK8
Cyclin-dependent kinase 8

1

0

High-throughput

0.513

High

594843

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.513

High

594844

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

0

High-throughput

0.513

High

594850

SLF2
SMC5-SMC6 complex localization factor protein 2

1

0

High-throughput

0.513

High

594867

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

0

High-throughput

0.513

High

474456

VIME
Vimentin

1

0

High-throughput

0.493

High

594859

DJC17
DnaJ homolog subfamily C member 17

1

1

High-throughput

0.489

High

594868

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

319368

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

351075

ECD
Protein ecdysoneless homolog

1

1

High-throughput

0.479

High

587857

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

594827

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

594830

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

594855

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

1

High-throughput

0.479

High

594862

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

440341

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.458

High

594832

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.458

High

594834

CRK
Adapter molecule crk

1

0

High-throughput

0.458

High

594838

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

594841

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

594846

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

594852

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

594856

THOC1
THO complex subunit 1

1

0

High-throughput

0.458

High

594847

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

594851

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.426

High

594858

GINM1
Glycoprotein integral membrane protein 1

3

0

High-throughput

0.347

High

594842

ELAV2
ELAV-like protein 2

2

0

High-throughput

0.328

High

594828

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

594860

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

594863

CTNA3
Catenin alpha-3

1

0

High-throughput

0.279

Low

105269

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

594836

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.232

Low

594853

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025