Interactor 1: CDK5 (Q03114)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Interactor 2: NTRK3 (Q03351)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.710

The method score is based on:

Property Details
Experiments 17341134
Identification Methods protein kinase assay, anti bait coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~Pkinase, PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0001764 - neuron migration
GO:0002039 - p53 binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 292
Rn

1 864
+ Hs
+ Mm
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+ Rn
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+ Hs
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+ Dm
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+ Hs

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Last updated: 15 Jul 2024