Interactor 1: EPHA4 (Q03137)
Ephrin type-A receptor 4 (EC 2.7.10.1) (Tyrosine-protein kinase receptor MPK-3) (Tyrosine-protein kinase receptor SEK-1)
Gene: EPHA4

Interactor 2: CHIN (Q91V57)
N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2)
Gene: Chn1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 17719550
Identification Methods anti bait coimmunoprecipitation, pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~fn3, C1_1~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0008045 - motor neuron axon guidance
GO:0043087 - regulation of GTPase activity
GO:0046875 - ephrin receptor binding
GO:0048013 - ephrin receptor signaling pathway
GO:0050770 - regulation of axonogenesis
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 986
Mm

1 459
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024