HitPredict

Interactor 1: KMT2A (Q03164)
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
Gene: KMT2A

Interactor 2: NUP50 (Q9UKX7)
Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50)
Gene: NUP50

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 3969 Hs			1 468
+	Hs
		1080468 EZH2_HUMAN (3450-3951): 9.4e-105: 357: 18.54		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Hs
		1317725 NSD3_HUMAN (3750-3968): 2.19e-56: 220: 25.68		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Hs
		165734 SET1A_HUMAN (3695-3969): 8.18e-56: 218: 34.58		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Hs
		796752 EZH2_HUMAN (3450-3951): 9.4e-105: 357: 18.54		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38
+	Hs
		834755 EZH2_HUMAN (3450-3951): 9.4e-105: 357: 18.54		RBP2_HUMAN (212-468): 1.6e-36: 146: 17.60
+	Hs
		1302935 MINT_HUMAN (418-1102): 7.18e-09: 64.7: 11.18		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00