HitPredict

Interactor 1: PPARD (Q03181)
Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta)
Gene: PPARD

Interactor 2: TBL3 (Q12788)
Transducin beta-like protein 3 (WD repeat-containing protein SAZD)
Gene: TBL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 808
+	Hs
		369488 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TBL3_HUMAN (1-808): 0: 635: 100.00
+	Hs
		152871 PPARD_HUMAN (1-441): 5.15e-125: 371: 100.00		APAF_HUMAN (329-768): 5.07e-68: 247: 16.46
+	Hs
		740487 PPARG_HUMAN (13-441): 3.64e-114: 346: 57.28		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Hs
		369305 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Mm
		903664 ERR2_MOUSE (2-438): 7.78e-98: 301: 20.31		WDR5_MOUSE (2-277): 3.62e-70: 235: 15.19
+	Hs
		782513 HNF4A_HUMAN (54-437): 8.86e-100: 307: 21.30		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Hs
		370071 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		GEMI5_HUMAN (234-739): 6.31e-54: 205: 12.88
+	Hs
		903650 NR2E3_HUMAN (63-439): 1.43e-94: 292: 25.53		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Hs
		369932 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		WDR5B_HUMAN (3-222): 1.96e-54: 193: 16.89
+	Hs
		369648 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		PWP2_HUMAN (3-331): 2.47e-29: 127: 15.79
+	Dm
		709192 ECR_DROME (39-437): 8.64e-99: 316: 27.88		Q9VDE3_DROME (334-632): 5.6e-23: 105: 25.48
+	Hs
		370713 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		WDR3_HUMAN (2-94): 8.52e-16: 84.1: 10.64
+	Hs
		267731 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TAF5L_HUMAN (77-318): 1.83e-14: 79.3: 27.27
+	Hs
		267744 HNF4A_HUMAN (54-437): 8.86e-100: 307: 21.30		TAF5L_HUMAN (77-318): 1.83e-14: 79.3: 27.27
+	Hs
		369669 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TAF5_HUMAN (74-224): 5.48e-11: 68.2: 25.17
+	Hs
		782550 HNF4A_HUMAN (54-437): 8.86e-100: 307: 21.30		TAF5_HUMAN (74-224): 5.48e-11: 68.2: 25.17