HitPredict

Interactor 1: PPARD (Q03181)
Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta)
Gene: PPARD

Interactor 2: TRI32 (Q13049)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
Gene: TRIM32

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 653
+	Hs
		587161 RXRA_HUMAN (4-438): 9.66e-111: 335: 24.77		TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00
+	Hs
		369510 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00
+	Hs
		487958 RARA_HUMAN (20-439): 9.06e-98: 302: 25.94		TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00
+	Hs
		536747 PPARG_HUMAN (13-441): 3.64e-114: 346: 57.28		TRI27_HUMAN (6-486): 2.41e-106: 333: 13.43
+	Hs
		262145 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TRIM3_HUMAN (1-645): 1.53e-106: 340: 17.03
+	Hs
		368914 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TRI27_HUMAN (6-486): 2.41e-106: 333: 13.43
+	Hs
		536736 RXRB_HUMAN (29-438): 1.2e-100: 312: 25.00		TRI27_HUMAN (6-486): 2.41e-106: 333: 13.43
+	Hs
		370187 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TRI11_HUMAN (1-470): 1.08e-97: 309: 16.03
+	Hs
		242818 PPARG_HUMAN (13-441): 3.64e-114: 346: 57.28		TRI13_HUMAN (11-293): 3.06e-75: 248: 23.00
+	Hs
		370324 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TRI56_HUMAN (20-644): 3.95e-75: 257: 14.82
+	Hs
		369497 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TRI26_HUMAN (6-377): 1.71e-56: 202: 18.54
+	Hs
		659746 RXRB_HUMAN (29-438): 1.2e-100: 312: 25.00		TRIM1_HUMAN (2-250): 1.5e-48: 183: 22.82
+	Hs
		265849 NR1I2_HUMAN (74-437): 2.75e-30: 123: 25.98		RO52_HUMAN (6-470): 1.76e-111: 345: 14.62
+	Hs
		536883 Q6NSM0_HUMAN (74-187): 1.16e-34: 135: 51.72		TRI27_HUMAN (6-486): 2.41e-106: 333: 13.43
+	Hs
		536836 NR1D2_HUMAN (257-421): 2.31e-25: 110: 39.16		TRI27_HUMAN (6-486): 2.41e-106: 333: 13.43
+	Hs
		242811 NR4A1_HUMAN (38-439): 6.71e-30: 124: 29.26		TRI13_HUMAN (11-293): 3.06e-75: 248: 23.00
+	Hs
		1155959 Q6NSM0_HUMAN (74-187): 1.16e-34: 135: 51.72		TRIM1_HUMAN (2-250): 1.5e-48: 183: 22.82
+	Hs
		1061371 NR1D2_HUMAN (257-421): 2.31e-25: 110: 39.16		TRIM1_HUMAN (2-250): 1.5e-48: 183: 22.82