HitPredict

Interactor 1: PPARD (Q03181)
Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta)
Gene: PPARD

Interactor 2: SAMD1 (Q6SPF0)
Sterile alpha motif domain-containing protein 1 (SAM domain-containing protein 1) (Atherin)
Gene: SAMD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 538
+	Hs
		369848 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		SAMD1_HUMAN (1-538): 1.87e-41: 158: 100.00
+	Hs
		740556 PPARG_HUMAN (13-441): 3.64e-114: 346: 57.28		KMT2C_HUMAN (4-472): 2.2e-22: 104: 12.45
+	Hs
		554279 PPARG_HUMAN (13-441): 3.64e-114: 346: 57.28		MUC1_HUMAN (39-490): 1.64e-19: 94.9: 11.79
+	Hs
		257541 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		ANR17_HUMAN (66-432): 9.29e-27: 117: 15.05
+	Hs
		370040 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		KMT2C_HUMAN (4-472): 2.2e-22: 104: 12.45
+	Hs
		368927 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		MUC1_HUMAN (39-490): 1.64e-19: 94.9: 11.79
+	Hs
		782595 HNF4A_HUMAN (54-437): 8.86e-100: 307: 21.30		KMT2C_HUMAN (4-472): 2.2e-22: 104: 12.45
+	Hs
		369005 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		RPB1_HUMAN (133-246): 5.11e-15: 80.7: 14.91
+	Hs
		509903 VDR_HUMAN (57-439): 7.97e-102: 311: 24.16		RPB1_HUMAN (133-246): 5.11e-15: 80.7: 14.91
+	Hs
		370105 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		TITIN_HUMAN (14-387): 8.98e-11: 67.1: 14.02
+	Mm
		444965 ERR2_MOUSE (2-438): 7.78e-98: 301: 20.31		RPB1_MOUSE (133-246): 9.46e-15: 80: 14.91
+	Mm
		139998 ERR2_MOUSE (2-438): 7.78e-98: 301: 20.31		O08847_MOUSE (85-177): 2.91e-13: 75: 20.43
+	Mm
		581219 THB_MOUSE (6-439): 4.08e-95: 295: 23.87		NFH_MOUSE (3-454): 7.89e-15: 79.9: 13.20
+	Mm
		101828 ERR2_MOUSE (2-438): 7.78e-98: 301: 20.31		F8WI37_MOUSE (11-443): 9.01e-12: 70.2: 10.30
+	Mm
		1142676 ERR2_MOUSE (2-438): 7.78e-98: 301: 20.31		KMT2C_MOUSE (11-443): 9.01e-12: 70.2: 10.30
+	Mm
		1142660 ERR2_MOUSE (2-438): 7.78e-98: 301: 20.31		KMT2D_MOUSE (2-459): 3.21e-09: 62.1: 11.52