HitPredict

Interactor 1: PPARD (Q03181)
Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta)
Gene: PPARD

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 1072
+	Hs
		370179 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		RNF31_HUMAN (1-1072): 0: 1111: 100.00
+	Dm
		709177 ECR_DROME (39-437): 8.64e-99: 316: 27.88		ARI1_DROME (590-1058): 5.57e-113: 361: 14.20
+	Hs
		509991 VDR_HUMAN (57-439): 7.97e-102: 311: 24.16		RNF14_HUMAN (657-924): 3.51e-65: 230: 14.09
+	Hs
		369196 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		NU153_HUMAN (89-504): 1.97e-28: 126: 13.40
+	Hs
		369197 ESR1_HUMAN (1-437): 1.92e-102: 318: 19.82		RBP2_HUMAN (287-482): 4.73e-27: 122: 15.98
+	Hs
		611519 NR4A1_HUMAN (38-439): 6.71e-30: 124: 29.26		AKIB1_HUMAN (431-1040): 1.61e-81: 290: 12.26
+	Hs
		782684 HNF4A_HUMAN (54-437): 8.86e-100: 307: 21.30		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		488029 RARA_HUMAN (20-439): 9.06e-98: 302: 25.94		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44