HitPredict

Interactor 1: VPS72 (Q03388)
Vacuolar protein sorting-associated protein 72 (SWR complex protein 2)
Gene: VPS72

Interactor 2: ARP6 (Q12509)
Actin-like protein ARP6
Gene: ARP6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.873

Property	Details
Experiments	16299513, 37968396, 14690608, 21179020
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~YL1_C
Common GO terms	GO:0000785 - chromatin GO:0000812 - Swr1 complex GO:0005737 - cytoplasm GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 795 Sc			1 438
+	Sc
		887659 VPS72_YEAST (1-795): 0: 966: 100.00		ACT_YEAST (2-432): 0: 529: 21.67
+	Hs
		891791 VPS72_HUMAN (16-304): 1.46e-46: 172: 20.76		ACTB_HUMAN (2-432): 0: 536: 19.87
+	Dm
		54871 A1ZA72_DROME (60-483): 1.16e-09: 64.6: 13.10		ACT6_DROME (2-432): 0: 531: 19.87
+	Sp
		292785 VPS72_SCHPO (14-305): 2.47e-36: 141: 19.18		ARP6_SCHPO (1-431): 3.19e-67: 221: 32.21
+	Hs
		1079901 VPS72_HUMAN (16-304): 1.46e-46: 172: 20.76		ARP6_HUMAN (6-427): 4.31e-49: 173: 29.45
+	Sp
		501587 VPS72_SCHPO (14-305): 2.47e-36: 141: 19.18		ACT_SCHPO (2-424): 8.21e-19: 89.4: 23.53