Interactor 1: KIME (Q03426)
Mevalonate kinase (MK) (EC 2.7.1.36)
Gene: MVK

Interactor 2: KIME (Q03426)
Mevalonate kinase (MK) (EC 2.7.1.36)
Gene: MVK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 25416956, 16189514, 26871637, 32296183, 25502805, 31515488, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GHMP_kinases_C~GHMP_kinases_C, GHMP_kinases_C~GHMP_kinases_N, GHMP_kinases_N~GHMP_kinases_N
Common GO terms GO:0000287 - magnesium ion binding
GO:0004496 - mevalonate kinase activity
GO:0005524 - ATP binding
GO:0005777 - peroxisome
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 396
Hs

1 396
+ Hs
+ Rn
+ Sc

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Last updated: 15 Jul 2024