HitPredict

Interactor 1: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Interactor 2: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	26030138, 31722399, 33961781
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1493 Hs			1 425
+	Hs
		976460 ERCC6_HUMAN (1-1493): 0: 1168: 100.00		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		997824 CHD5_HUMAN (300-1446): 0: 783: 19.15		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		997936 CHD7_HUMAN (3-1479): 0: 774: 17.81		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		997726 CHD4_HUMAN (303-1439): 0: 766: 18.35		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		1083322 CHD5_HUMAN (300-1446): 0: 783: 19.15		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		997695 CHD3_HUMAN (303-1446): 0: 759: 19.68		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		484255 ERPG3_HUMAN (1-487): 0: 753: 96.12		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		1059641 CHD4_HUMAN (303-1439): 0: 766: 18.35		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		1018507 CHD3_HUMAN (303-1446): 0: 759: 19.68		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		658658 SMCA1_HUMAN (369-1372): 0: 700: 20.58		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		229377 SMCA5_HUMAN (368-1383): 0: 698: 20.75		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		658682 SMCA1_HUMAN (369-1372): 0: 700: 20.58		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		846946 SMCA4_HUMAN (228-1324): 0: 677: 19.90		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		229413 SMCA5_HUMAN (368-1383): 0: 698: 20.75		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		903234 CHD4_HUMAN (303-1439): 0: 766: 18.35		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		1059830 CHD4_HUMAN (303-1439): 0: 766: 18.35		GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56
+	Hs
		903535 CHD8_HUMAN (2-1474): 0: 725: 16.46		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		1018714 CHD3_HUMAN (303-1446): 0: 759: 19.68		NLE1_HUMAN (8-106): 1.77e-21: 98.3: 10.58
+	Dm
		332768 CHDM_DROME (281-1433): 0: 679: 17.12		CAF1_DROME (226-419): 3.68e-29: 119: 18.36
+	Ce
		954000 CHD3_CAEEL (245-1380): 0: 684: 18.74		LIN53_CAEEL (272-421): 6.33e-22: 99.1: 21.52