HitPredict

Interactor 1: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Interactor 2: CTR9 (Q6PD62)
RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1)
Gene: CTR9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26030138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1493 Hs			1 1173
+	Hs
		1059682 CHD4_HUMAN (303-1439): 0: 766: 18.35		CTR9_HUMAN (1-1173): 0: 592: 100.00
+	Hs
		1018538 CHD3_HUMAN (303-1446): 0: 759: 19.68		CTR9_HUMAN (1-1173): 0: 592: 100.00
+	Hs
		1160977 CHD8_HUMAN (2-1474): 0: 725: 16.46		CTR9_HUMAN (1-1173): 0: 592: 100.00
+	Sc
		697422 CHD1_YEAST (409-1426): 0: 748: 20.90		CTR9_YEAST (5-982): 1.96e-57: 218: 19.58
+	Hs
		300144 CHD4_HUMAN (303-1439): 0: 766: 18.35		PRP6_HUMAN (32-285): 7.01e-11: 68.7: 12.02
+	Hs
		300125 CHD3_HUMAN (303-1446): 0: 759: 19.68		PRP6_HUMAN (32-285): 7.01e-11: 68.7: 12.02
+	Hs
		183086 SMCA4_HUMAN (228-1324): 0: 677: 19.90		KDM6A_HUMAN (4-261): 4.06e-20: 99.1: 11.03
+	Mm
		251035 SMCA4_MOUSE (228-1233): 0: 674: 19.35		KDM6A_MOUSE (4-261): 1.71e-20: 100: 11.03
+	Dm
		332887 CHDM_DROME (281-1433): 0: 679: 17.12		Q9VSK6_DROME (596-955): 7.82e-16: 85.3: 15.00
+	Hs
		300086 SMCA2_HUMAN (228-1247): 0: 660: 19.72		PRP6_HUMAN (32-285): 7.01e-11: 68.7: 12.02
+	Sc
		772484 RAD26_YEAST (1190-1456): 1.02e-40: 166: 21.17		CTR9_YEAST (5-982): 1.96e-57: 218: 19.58