Interactor 1: CEF1 (Q03654)
Pre-mRNA-splicing factor CEF1 (PRP nineteen-associated complex protein 85) (PRP19-associated complex protein 85)
Gene: CEF1

Interactor 2: CLF1 (Q12309)
Pre-mRNA-splicing factor CLF1 (Crooked neck-like factor 1) (PRP19-associated complex protein 77) (Synthetic lethal with CDC40 protein 3)
Gene: CLF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 11842115, 11102353, 11805826, 11884590, 16429126, 29146870, 30879786, 19617314, 12509417, 37968396
Identification Methods two hybrid, coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HAT~Myb_Cef
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0071006 - U2-type catalytic step 1 spliceosome
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 590
Sc

1 687
+ Sc
+ Hs
+ Sp
+ Dm
+ Dm
+ Sp
+ Hs
+ At
+ Hs
+ Hs
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024