Interactor 1: HPRT (Q04178)
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) (Bypass of repression by adenine protein 6)
Gene: HPT1

Interactor 2: HPRT (Q04178)
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) (Bypass of repression by adenine protein 6)
Gene: HPT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.828

The method score is based on:

Property Details
Experiments 18719252, 22610485, unassigned1933
Identification Methods two hybrid, x-ray crystallography, dihydrofolate reductase reconstruction
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pribosyltran~Pribosyltran
Common GO terms GO:0000166 - nucleotide binding
GO:0004422 - hypoxanthine phosphoribosyltransferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006166 - purine ribonucleoside salvage
and 6 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 221
Sc

1 221
+ Sc
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024