HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	19270718, 24442433, 19327355
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 745
+	Hs
		587564 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		587565 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		587563 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		961384 NFKB2_HUMAN (7-409): 7.21e-137: 420: 34.75		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		961385 NFKB2_HUMAN (7-409): 7.21e-137: 420: 34.75		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		961383 NFKB2_HUMAN (7-409): 7.21e-137: 420: 34.75		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		1021731 NFAC3_HUMAN (4-522): 1.3e-119: 380: 19.26		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		587664 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		CUL5_HUMAN (7-745): 0: 627: 26.69