HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: IASPP (Q8WUF5)
RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein)
Gene: PPP1R13L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 10336463, 12134007
Identification Methods two hybrid, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~RHD_dimer
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 551
Hs

1 828
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Last updated: 15 Jul 2024