HitPredict

Interactor 1: UTP15 (Q04305)
U3 small nucleolar RNA-associated protein 15 (U3 snoRNA-associated protein 15) (U three protein 15) (U3 protein 15 required for transcription) (t-UTP15)
Gene: UTP15

Interactor 2: NOP58 (Q12499)
Nucleolar protein 58 (Nucleolar protein 5)
Gene: NOP58

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	37968396, 12068309, 12150911, 16429126, 21558325
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome and 1 others more... GO:0032040 - small-subunit processome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 513 Sc			1 511
+	Sc
		979266 UTP15_YEAST (1-513): 1.38e-108: 334: 100.00		NOP56_YEAST (1-473): 1.17e-170: 493: 37.58
+	Hs
		133597 FBXW7_HUMAN (5-371): 7.23e-77: 257: 14.47		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		1281498 FBXW7_HUMAN (5-371): 7.23e-77: 257: 14.47		NOP58_HUMAN (2-506): 0: 546: 45.69
+	Hs
		133611 SNR40_HUMAN (2-105): 9.6e-19: 89.5: 10.44		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		1288400 SNR40_HUMAN (2-105): 9.6e-19: 89.5: 10.44		NOP58_HUMAN (2-506): 0: 546: 45.69
+	Hs
		133462 TBL3_HUMAN (262-421): 2.27e-11: 68.3: 10.37		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		903625 WDR5_HUMAN (333-420): 2.73e-12: 69.9: 10.23		NOP58_HUMAN (2-506): 0: 546: 45.69
+	Hs
		1262976 SNR40_HUMAN (2-105): 9.6e-19: 89.5: 10.44		PRP31_HUMAN (155-454): 6.6e-105: 324: 22.08
+	Hs
		903389 WDR5_HUMAN (333-420): 2.73e-12: 69.9: 10.23		PRP31_HUMAN (155-454): 6.6e-105: 324: 22.08