HitPredict

Interactor 1: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Interactor 2: T22D1 (Q15714)
TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)
Gene: TSC22D1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 770 Hs			1 1073
+	Hs
		577620 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71
+	Hs
		152632 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60
+	Hs
		980830 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		CBP_HUMAN (362-900): 7.28e-09: 62.4: 12.04
+	Hs
		154684 GNB5_HUMAN (607-768): 4.77e-27: 116: 17.92		T22D1_HUMAN (1-1073): 7.61e-82: 291: 100.00
+	Hs
		993655 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15
+	Hs
		921573 GBB2_HUMAN (673-769): 4.45e-14: 76.4: 14.29		T22D1_HUMAN (1-1073): 7.61e-82: 291: 100.00
+	Hs
		577699 NLE1_HUMAN (257-684): 2.37e-65: 227: 11.13		SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71
+	Hs
		1318191 TBL1R_HUMAN (558-769): 4.54e-47: 177: 15.65		T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15
+	Hs
		245651 TBL1X_HUMAN (569-769): 5.32e-46: 175: 16.51		T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15
+	Hs
		903374 WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37		KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46
+	Mm
		903669 WDR5_MOUSE (655-769): 2.57e-36: 141: 21.37		KMT2C_MOUSE (291-1072): 3.73e-09: 63.5: 9.47
+	Hs
		152622 WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37		KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60
+	Hs
		903405 WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37		CBP_HUMAN (362-900): 7.28e-09: 62.4: 12.04
+	Hs
		152663 WDR5B_HUMAN (655-769): 2.42e-34: 136: 22.22		KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60
+	Dm
		1370283 Q9VT91_DROME (578-767): 1.23e-11: 70.5: 25.25		Q9VLS7_DROME (1-689): 2.91e-10: 67: 9.43
+	Hs
		577684 SNR40_HUMAN (507-675): 1.08e-09: 62.8: 28.18		SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71
+	Hs
		1153497 SNR40_HUMAN (507-675): 1.08e-09: 62.8: 28.18		ADNP2_HUMAN (653-1067): 2.23e-09: 63.7: 13.00