Protein: PUR4
Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase)

Gene: PUR4, ADE6
Organism: Saccharomyces cerevisiae S288C
Interactions: 35
UniProt ID: P38972

Gene Ontology (top 5):
GO:0004642 - phosphoribosylformylglycinamidine synthase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006164 - purine nucleotide biosynthetic process
GO:0006189 - 'de novo' IMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

543731

HSC82
ATP-dependent molecular chaperone HSC82

3

1

High-throughput

0.633

High

758594

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

491222

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.552

High

758597

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

0

High-throughput

0.493

High

366287

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

703617

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

758599

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

758601

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

758604

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

537416

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

662220

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688242

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

691049

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.458

High

753804

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

758596

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

758598

ESP1
Separin

1

0

High-throughput

0.458

High

758602

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

478192

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.445

High

493967

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

511310

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

633221

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

680705

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

694699

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

695968

HSP79
Heat shock protein homolog SSE2

1

4

High-throughput

0.445

High

758593

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

628046

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

556044

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

758595

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.426

High

758600

VAC14
Vacuole morphology and inheritance protein 14

2

0

High-throughput

0.314

High

586404

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.279

Low

655709

PRP45
Pre-mRNA-processing protein 45

1

0

Small-scale

0.251

Low

715327

SPT7
Transcriptional activator SPT7

1

0

High-throughput

0.249

Low

745654

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

756915

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

758603

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024