HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 772 Hs			1 1281
+	Hs
		554432 TLE3_HUMAN (1-772): 0: 583: 100.00		GATA1_HUMAN (804-1046): 1.3e-37: 148: 17.55
+	Hs
		620482 TLE3_HUMAN (1-772): 0: 583: 100.00		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		620330 TLE3_HUMAN (1-772): 0: 583: 100.00		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Hs
		554431 TLE1_HUMAN (1-772): 0: 538: 77.42		GATA1_HUMAN (804-1046): 1.3e-37: 148: 17.55
+	Hs
		620481 TLE1_HUMAN (1-772): 0: 538: 77.42		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		993415 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		620329 TLE1_HUMAN (1-772): 0: 538: 77.42		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Hs
		620331 TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Hs
		993645 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		1033680 POC1A_HUMAN (325-603): 2.33e-51: 186: 14.59		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		1033727 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		554438 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		GATA1_HUMAN (804-1046): 1.3e-37: 148: 17.55
+	Hs
		1033684 POC1B_HUMAN (290-512): 1.47e-23: 106: 9.78		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		1318186 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		620487 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		620335 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Hs
		799000 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Hs
		620569 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		620419 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Sp
		999839 TUP11_SCHPO (22-606): 7.76e-53: 195: 10.78		FEP1_SCHPO (893-1036): 3.4e-12: 72.9: 21.52