Protein: PALB2
Partner and localizer of BRCA2

Gene: PALB2
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q86YC2

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0001756 - somitogenesis
GO:0001833 - inner cell mass cell proliferation
GO:0003677 - DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

904327

BRCA2
Breast cancer type 2 susceptibility protein

29

1

Small-scale

0.770

High

799270

BRCA1
Breast cancer type 1 susceptibility protein

19

1

Small-scale

0.766

High

1294965

MO4L1
Mortality factor 4-like protein 1

17

1

Small-scale

0.765

High

1055938

RAD51
DNA repair protein RAD51 homolog 1

15

3

Small-scale

0.763

High

1136810

MO4L2
Mortality factor 4-like protein 2

8

1

Small-scale

0.750

High

1121446

KEAP1
Kelch-like ECH-associated protein 1

11

0

Small-scale

0.727

High

1294942

PALB2
Partner and localizer of BRCA2

4

1

Small-scale

0.683

High

219083

RA51C
DNA repair protein RAD51 homolog 3

1

3

Small-scale

0.597

High

1294961

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

2

0

Small-scale

0.592

High

907490

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

2

Small-scale

0.586

High

979933

H4
Histone H4

2

0

Small-scale

0.569

High

998504

H31
Histone H3.1

2

0

Small-scale

0.569

High

219975

XRCC3
DNA repair protein XRCC3

1

3

Small-scale

0.568

High

1294969

POLH
DNA polymerase eta

1

0

Small-scale

0.561

High

1294968

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

1

Small-scale

0.561

High

1294943

RN168
E3 ubiquitin-protein ligase RNF168

1

0

Small-scale

0.537

High

833751

KDM5C
Lysine-specific demethylase 5C

1

1

High-throughput

0.536

High

1294944

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.536

High

350064

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.518

High

1092418

IL24
Interleukin-24

1

0

High-throughput

0.518

High

1197218

GREB1
Protein GREB1

1

0

High-throughput

0.518

High

1289784

CASZ1
Zinc finger protein castor homolog 1

1

0

High-throughput

0.518

High

1294946

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.518

High

1294947

KLK6
Kallikrein-6

1

0

High-throughput

0.518

High

1294956

PRD14
PR domain zinc finger protein 14

1

0

High-throughput

0.518

High

1294959

BCAS3
BCAS3 microtubule associated cell migration factor

1

0

High-throughput

0.518

High

1294966

ERRFI
ERBB receptor feedback inhibitor 1

1

0

High-throughput

0.518

High

390091

ALBU
Albumin

1

0

High-throughput

0.513

High

1113605

CUL3
Cullin-3

1

0

Small-scale

0.513

High

1294953

CTIP
DNA endonuclease RBBP8

1

0

Small-scale

0.513

High

1294954

FANCJ
Fanconi anemia group J protein

1

0

Small-scale

0.513

High

288458

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

2

Small-scale

0.501

High

754901

H2B1B
Histone H2B type 1-B

1

2

Small-scale

0.501

High

909076

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.489

High

1294948

R51A1
RAD51-associated protein 1

1

0

Small-scale

0.480

High

143098

NFIB
Nuclear factor 1 B-type

1

1

High-throughput

0.479

High

711831

KDM5A
Lysine-specific demethylase 5A

1

1

High-throughput

0.479

High

980900

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

1087849

NFIA
Nuclear factor 1 A-type

1

1

High-throughput

0.479

High

1163034

H2B2E
Histone H2B type 2-E

1

2

Small-scale

0.479

High

1294970

MOFA1
MORF4 family-associated protein 1

1

1

High-throughput

0.479

High

184725

ATX7
Ataxin-7

1

0

Small-scale

0.458

High

246731

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

274349

SIN3B
Paired amphipathic helix protein Sin3b

1

0

High-throughput

0.458

High

292914

RNH2A
Ribonuclease H2 subunit A

1

0

Small-scale

0.458

High

462498

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

Small-scale

0.458

High

552832

TPR
Nucleoprotein TPR

1

0

High-throughput

0.458

High

589082

RFA2
Replication protein A 32 kDa subunit

1

0

Small-scale

0.458

High

704751

ERCC5
DNA excision repair protein ERCC-5

1

0

Small-scale

0.458

High

887004

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

1045473

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1109862

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1135627

AT7L3
Ataxin-7-like protein 3

1

0

Small-scale

0.458

High

1278946

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

0

High-throughput

0.458

High

1279413

DPOLN
DNA polymerase nu

1

0

Small-scale

0.458

High

1281549

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1294945

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1294950

SYNM
Asparaginyl-tRNA synthetase

1

0

High-throughput

0.458

High

1294952

PHF12
PHD finger protein 12

1

0

High-throughput

0.458

High

1294957

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1294958

BRD8
Bromodomain-containing protein 8

1

0

High-throughput

0.458

High

1294960

ENY2
Transcription and mRNA export factor ENY2

1

0

Small-scale

0.458

High

1294962

MRGBP
MRG/MORF4L-binding protein

1

0

High-throughput

0.458

High

1294967

RCOR1
REST corepressor 1

1

0

High-throughput

0.458

High

1294949

MR1L1
MORF4 family-associated protein 1-like 1

1

1

High-throughput

0.437

High

1294963

MS18A
Protein Mis18-alpha

1

0

High-throughput

0.426

High

332669

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.282

High

341097

DIRA3
GTP-binding protein Di-Ras3

1

0

High-throughput

0.282

High

539927

ARY2
Arylamine N-acetyltransferase 2

1

0

High-throughput

0.282

High

562899

CCL5
C-C motif chemokine 5

1

0

High-throughput

0.282

High

787673

SPB5
Serpin B5

1

0

High-throughput

0.282

High

1128915

I13R2
Interleukin-13 receptor subunit alpha-2

1

0

High-throughput

0.282

High

1154318

CYTM
Cystatin-M

1

0

High-throughput

0.282

High

1294951

LRAT2
Protein LRATD2

1

0

High-throughput

0.282

High

1294955

RHBT2
Rho-related BTB domain-containing protein 2

1

0

High-throughput

0.282

High

1294964

MRC2
C-type mannose receptor 2

1

0

High-throughput

0.282

High

287326

RF1M
Peptide chain release factor 1, mitochondrial

1

0

High-throughput

0.279

Low

706204

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1042029

LMNB2
Lamin-B2

1

0

High-throughput

0.279

Low

457110

CAN1
Calpain-1 catalytic subunit

1

0

Small-scale

0.249

Low

992025

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.249

Low

1252111

SYNE3
Nesprin-3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025