HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: MYH4 (Q9Y623)
Myosin-4 (Myosin heavy chain 2b) (MyHC-2b) (Myosin heavy chain 4) (Myosin heavy chain IIb) (MyHC-IIb) (Myosin heavy chain, skeletal muscle, fetal)
Gene: MYH4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 772 Hs			1 1939
+	Hs
		522544 TLE3_HUMAN (1-772): 0: 583: 100.00		MYH1_HUMAN (1-1939): 0: 1207: 94.07
+	Hs
		980905 TLE3_HUMAN (1-772): 0: 583: 100.00		MYH2_HUMAN (1-1939): 0: 1187: 91.50
+	Hs
		522607 TLE3_HUMAN (1-772): 0: 583: 100.00		MYH7_HUMAN (717-1818): 1.08e-65: 249: 16.17
+	Hs
		528407 TLE3_HUMAN (1-772): 0: 583: 100.00		MYH8_HUMAN (985-1939): 2.26e-59: 229: 17.81
+	Hs
		502910 TLE3_HUMAN (1-772): 0: 583: 100.00		MYH3_HUMAN (1519-1939): 9.2e-23: 108: 14.49
+	Hs
		64592 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		MYH7B_HUMAN (727-1615): 7.74e-43: 175: 16.08
+	Hs
		728492 POC1A_HUMAN (325-603): 2.33e-51: 186: 14.59		MYH11_HUMAN (724-1785): 1.11e-60: 233: 18.21
+	Hs
		724753 GBB2_HUMAN (688-771): 3.6e-14: 76.4: 16.47		MYH9_HUMAN (985-1939): 1.02e-61: 236: 17.93
+	Hs
		903334 WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12		MYH14_HUMAN (782-1411): 5.92e-24: 113: 15.12