HitPredict

Interactor 1: TLE4 (Q04727)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Interactor 2: FOXL1 (Q12952)
Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7)
Gene: FOXL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 773 Hs			1 345
+	Hs
		980596 TLE1_HUMAN (8-773): 0: 580: 86.27		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		980742 TLE3_HUMAN (8-773): 0: 539: 80.90		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		877703 TLE1_HUMAN (8-773): 0: 580: 86.27		FOXA1_HUMAN (5-320): 1.41e-80: 255: 30.27
+	Hs
		980951 TLE4_HUMAN (1-773): 0: 622: 100.00		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		877704 TLE3_HUMAN (8-773): 0: 539: 80.90		FOXA1_HUMAN (5-320): 1.41e-80: 255: 30.27
+	Hs
		980930 TLE4_HUMAN (1-773): 0: 622: 100.00		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Hs
		877602 TLE1_HUMAN (8-773): 0: 580: 86.27		FOXG1_HUMAN (48-224): 2.13e-52: 182: 40.68
+	Hs
		980669 TLE1_HUMAN (8-773): 0: 580: 86.27		FOXA2_HUMAN (7-320): 8.22e-53: 182: 29.13
+	Hs
		877990 TLE1_HUMAN (8-773): 0: 580: 86.27		FOXA3_HUMAN (47-146): 1.57e-50: 173: 63.00
+	Hs
		980641 TLE1_HUMAN (8-773): 0: 580: 86.27		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		980595 TLE1_HUMAN (8-773): 0: 580: 86.27		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Mm
		1141982 TLE1_MOUSE (8-773): 0: 558: 85.77		FOXG1_MOUSE (5-224): 1.31e-50: 176: 33.64
+	Rn
		88552 D3ZCM7_RAT (8-773): 0: 556: 85.25		FOXG1_RAT (5-224): 1.63e-50: 176: 33.64
+	Hs
		980740 TLE3_HUMAN (8-773): 0: 539: 80.90		FOXC1_HUMAN (9-280): 1.15e-53: 186: 35.86
+	Hs
		877992 TLE3_HUMAN (8-773): 0: 539: 80.90		FOXA3_HUMAN (47-146): 1.57e-50: 173: 63.00
+	Hs
		980855 TLE3_HUMAN (8-773): 0: 539: 80.90		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		980741 TLE3_HUMAN (8-773): 0: 539: 80.90		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Hs
		877991 TLE2_HUMAN (8-773): 3.63e-157: 476: 65.19		FOXA3_HUMAN (47-146): 1.57e-50: 173: 63.00
+	Dm
		558388 GROU_DROME (8-773): 1.23e-144: 443: 59.14		Q961V5_DROME (33-187): 3.17e-48: 166: 42.58
+	Dm
		558360 GROU_DROME (8-773): 1.23e-144: 443: 59.14		SLP1_DROME (33-187): 1.16e-47: 165: 43.23