HitPredict

Interactor 1: TLE4 (Q04727)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Interactor 2: TBX20 (Q9UMR3)
T-box transcription factor TBX20 (T-box protein 20)
Gene: TBX20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 773 Hs			1 447
+	Hs
		980667 TLE1_HUMAN (8-773): 0: 580: 86.27		TBX20_HUMAN (1-447): 0: 530: 100.00
+	Hs
		980911 TLE3_HUMAN (8-773): 0: 539: 80.90		TBX20_HUMAN (1-447): 0: 530: 100.00
+	Hs
		171019 TLE4_HUMAN (1-773): 0: 622: 100.00		TBXT_HUMAN (81-415): 5.55e-110: 333: 34.81
+	Hs
		980935 TLE4_HUMAN (1-773): 0: 622: 100.00		TBR1_HUMAN (7-380): 4.56e-105: 328: 31.25
+	Hs
		980849 TLE3_HUMAN (8-773): 0: 539: 80.90		TBX15_HUMAN (11-429): 6.32e-127: 382: 38.98
+	Hs
		171017 TLE1_HUMAN (8-773): 0: 580: 86.27		TBXT_HUMAN (81-415): 5.55e-110: 333: 34.81
+	Hs
		980617 TLE1_HUMAN (8-773): 0: 580: 86.27		TBR1_HUMAN (7-380): 4.56e-105: 328: 31.25
+	Hs
		203427 TLE1_HUMAN (8-773): 0: 580: 86.27		TBX1_HUMAN (75-379): 1.12e-107: 326: 43.00
+	Hs
		1132995 Q5T3G3_HUMAN (8-237): 2.38e-122: 368: 76.03		TBX20_HUMAN (1-447): 0: 530: 100.00
+	Hs
		168131 TLE3_HUMAN (8-773): 0: 539: 80.90		TBX3_HUMAN (9-415): 2.97e-115: 356: 33.41
+	Hs
		1127614 Q5JSZ1_HUMAN (1-210): 4e-116: 351: 88.39		TBX20_HUMAN (1-447): 0: 530: 100.00
+	Hs
		171018 TLE3_HUMAN (8-773): 0: 539: 80.90		TBXT_HUMAN (81-415): 5.55e-110: 333: 34.81
+	Hs
		980761 TLE3_HUMAN (8-773): 0: 539: 80.90		TBR1_HUMAN (7-380): 4.56e-105: 328: 31.25
+	Dm
		558401 GROU_DROME (8-773): 1.23e-144: 443: 59.14		Q9VMR2_DROME (45-366): 4.08e-98: 307: 49.55
+	Hs
		168132 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		TBX3_HUMAN (9-415): 2.97e-115: 356: 33.41
+	Hs
		171021 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		TBXT_HUMAN (81-415): 5.55e-110: 333: 34.81
+	Ce
		137656 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		TBX1_CAEEL (80-311): 3.43e-104: 311: 47.41
+	Ce
		137670 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		TBX12_CAEEL (73-356): 5.95e-102: 309: 47.41
+	Ce
		137679 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		TBX2_CAEEL (83-418): 1.16e-100: 308: 36.31
+	Hs
		327890 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		TBX6_HUMAN (83-430): 6.71e-106: 322: 36.59