Protein: CKAP2
Cytoskeleton-associated protein 2 (CTCL tumor antigen se20-10) (Tumor- and microtubule-associated protein)

Gene: CKAP2
Organism: Homo sapiens
Interactions: 131
UniProt ID: Q8WWK9

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000922 - spindle pole
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

244861

TRAK2
Trafficking kinesin-binding protein 2

3

2

High-throughput

0.667

High

1152172

MARE1
Microtubule-associated protein RP/EB family member 1

2

3

High-throughput

0.611

High

422731

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.602

High

1132623

KIF22
Kinesin-like protein KIF22

2

0

High-throughput

0.602

High

122824

KIF2A
Kinesin-like protein KIF2A

2

0

High-throughput

0.585

High

1123737

DCTN1
Dynactin subunit 1

2

2

High-throughput

0.584

High

1143443

PCM1
Pericentriolar material 1 protein

2

1

High-throughput

0.584

High

1326282

NIN
Ninein

2

1

High-throughput

0.584

High

1359557

NINL
Ninein-like protein

2

1

High-throughput

0.584

High

1099740

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

0

High-throughput

0.576

High

396598

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

991894

DYLT1
Dynein light chain Tctex-type 1

2

0

High-throughput

0.559

High

1177978

MOONR
Protein moonraker

2

0

High-throughput

0.559

High

1182848

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

1

High-throughput

0.550

High

182339

WDR46
WD repeat-containing protein 46

1

1

High-throughput

0.536

High

287978

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

1

High-throughput

0.536

High

698332

MAP4
Microtubule-associated protein 4

1

1

High-throughput

0.536

High

993268

ACTG
Actin, cytoplasmic 2

1

1

High-throughput

0.536

High

1158802

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

1

High-throughput

0.536

High

1359544

PAK6
Serine/threonine-protein kinase PAK 6

1

1

High-throughput

0.536

High

1359555

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

1

High-throughput

0.536

High

1359551

HECD1
E3 ubiquitin-protein ligase HECTD1

2

1

High-throughput

0.533

High

1359552

FZR1
Fizzy-related protein homolog

2

1

Small-scale

0.533

High

923615

TTC3
E3 ubiquitin-protein ligase TTC3

1

0

High-throughput

0.518

High

239158

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.513

High

342984

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.513

High

445227

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

535342

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

715068

OAS2
2'-5'-oligoadenylate synthase 2

1

0

High-throughput

0.513

High

813174

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.513

High

1032374

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.513

High

1186287

MA7D1
MAP7 domain-containing protein 1

1

0

High-throughput

0.513

High

1193654

MAP9
Microtubule-associated protein 9

1

0

High-throughput

0.513

High

1198475

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.513

High

1198610

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.513

High

1199870

TYW2
tRNA wybutosine-synthesizing protein 2 homolog

1

0

High-throughput

0.513

High

1236115

CAN13
Calpain-13

1

0

High-throughput

0.513

High

1272245

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.513

High

1288211

LYRIC
Protein LYRIC

1

0

High-throughput

0.513

High

1359527

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1359529

LRC45
Leucine-rich repeat-containing protein 45

1

0

High-throughput

0.513

High

1359538

MIS12
Protein MIS12 homolog

1

0

High-throughput

0.513

High

1359558

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.513

High

1163091

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.489

High

1359559

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

372690

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406434

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

414298

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

872580

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

997056

TBA4A
Tubulin alpha-4A chain

1

1

High-throughput

0.479

High

1065744

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

1

High-throughput

0.479

High

1254825

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1259383

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.479

High

1322411

SPICE
Spindle and centriole-associated protein 1

1

1

High-throughput

0.479

High

1331533

CE120
Centrosomal protein of 120 kDa

1

2

High-throughput

0.479

High

1359526

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1359543

TRI36
E3 ubiquitin-protein ligase TRIM36

1

2

High-throughput

0.479

High

1359549

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1359554

MARE3
Microtubule-associated protein RP/EB family member 3

1

3

High-throughput

0.479

High

223213

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

245350

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.458

High

294096

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

363631

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

573185

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.458

High

591752

H2AX
Histone H2AX

1

0

High-throughput

0.458

High

605760

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

637149

CSRP1
Cysteine and glycine-rich protein 1

1

0

High-throughput

0.458

High

643955

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

721044

CLIP1
CAP-Gly domain-containing linker protein 1

1

0

High-throughput

0.458

High

831135

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

966673

1433G
14-3-3 protein gamma

1

0

High-throughput

0.458

High

1111626

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1123990

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.458

High

1210927

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.458

High

1215480

CE162
Centrosomal protein of 162 kDa

1

0

High-throughput

0.458

High

1280885

CNTRL
Centriolin

1

0

High-throughput

0.458

High

1291331

LCA5
Lebercilin

1

0

High-throughput

0.458

High

1294802

STX12
Syntaxin-12

1

0

High-throughput

0.458

High

1334155

POC1A
POC1 centriolar protein homolog A

1

0

High-throughput

0.458

High

1334696

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1359528

ARHG2
Rho guanine nucleotide exchange factor 2

1

0

Small-scale

0.458

High

1359532

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1359535

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

1359537

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

1359539

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.458

High

1359540

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1359542

CPAP
Centrosomal P4.1-associated protein

1

0

High-throughput

0.458

High

1359545

ANLN
Anillin

1

0

High-throughput

0.458

High

1359548

SEP10
Septin-10

1

0

High-throughput

0.458

High

1359550

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1359553

CC14A
Dual specificity protein phosphatase CDC14A

1

0

High-throughput

0.458

High

1359556

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.458

High

1209446

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

192505

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.437

High

218544

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

980958

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.437

High

1359560

INSI2
Insulin-induced gene 2 protein

1

1

High-throughput

0.437

High

430168

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1358010

TM171
Transmembrane protein 171

3

0

High-throughput

0.347

High

1359531

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.298

High

133548

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.279

Low

347210

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

505186

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

630327

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

1048611

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.279

Low

1094221

ACACA
Acetyl-CoA carboxylase 1

1

0

High-throughput

0.279

Low

1201248

ESCO2
N-acetyltransferase ESCO2

1

0

High-throughput

0.279

Low

1218819

FOCAD
Focadhesin

1

0

High-throughput

0.279

Low

1275786

TRPM8
Transient receptor potential cation channel subfamily M member 8

1

0

High-throughput

0.279

Low

1292762

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1359530

RMXL1
RNA binding motif protein, X-linked-like-1

1

0

High-throughput

0.279

Low

1359533

TMM74
Transmembrane protein 74

1

0

High-throughput

0.279

Low

1359534

PEO1
Twinkle mtDNA helicase

1

0

High-throughput

0.279

Low

1359536

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

High-throughput

0.279

Low

1359541

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

1359546

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.279

Low

144186

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

0

Small-scale

0.261

Low

353465

AGR2
Anterior gradient protein 2 homolog

1

0

Small-scale

0.251

Low

1359525

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

0

High-throughput

0.251

Low

336998

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.249

Low

365435

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.249

Low

475646

K1C19
Keratin, type I cytoskeletal 19

1

0

High-throughput

0.249

Low

589264

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696050

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768750

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

980050

H4
Histone H4

1

0

High-throughput

0.249

Low

1215733

RC3H1
Roquin-1

1

0

High-throughput

0.249

Low

1289487

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

1359547

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

379687

IGHA1
Immunoglobulin heavy constant alpha 1

1

0

High-throughput

0.232

Low

1243636

S27A1
Long-chain fatty acid transport protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025