Protein: S10A8
Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)

Gene: S10A8, S100A8
Organism: Homo sapiens
Interactions: 198
UniProt ID: P05109

Gene Ontology (top 5):
GO:0002523 - leukocyte migration involved in inflammatory response
GO:0002544 - chronic inflammatory response
GO:0002790 - peptide secretion
GO:0002793 - positive regulation of peptide secretion
GO:0005509 - calcium ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396665

S10A9
Protein S100-A9

10

18

Small-scale

0.970

High

385910

P53
Cellular tumor antigen p53

3

15

Small-scale

0.854

High

396664

S10A8
Protein S100-A8

2

18

Small-scale

0.767

High

396673

CFTR
Cystic fibrosis transmembrane conductance regulator

3

7

High-throughput

0.662

High

396726

MERTK
Tyrosine-protein kinase Mer

1

5

High-throughput

0.646

High

396764

CCYL1
Cyclin-Y-like protein 1

2

1

High-throughput

0.628

High

396666

ANXA2
Annexin A2

1

12

High-throughput

0.618

High

396688

S10A7
Protein S100-A7

1

18

High-throughput

0.618

High

396717

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

2

7

High-throughput

0.612

High

396686

SHC1
SHC-transforming protein 1

2

13

High-throughput

0.611

High

396798

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

2

18

High-throughput

0.611

High

396797

EFHD1
EF-hand domain-containing protein D1

2

0

High-throughput

0.602

High

368808

ESR1
Estrogen receptor

2

17

High-throughput

0.601

High

396683

CDK2
Cyclin-dependent kinase 2

2

10

High-throughput

0.584

High

396792

RNF5
E3 ubiquitin-protein ligase RNF5

2

7

Small-scale

0.584

High

396824

FBW1A
F-box/WD repeat-containing protein 1A

2

6

High-throughput

0.584

High

381739

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

Small-scale

0.579

High

396679

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.575

High

396745

SMTL2
Smoothelin-like protein 2

2

2

High-throughput

0.574

High

396812

TB22B
TBC1 domain family member 22B

2

6

High-throughput

0.574

High

164091

ARHGA
Rho guanine nucleotide exchange factor 10

2

4

High-throughput

0.571

High

396721

OCRL
Inositol polyphosphate 5-phosphatase OCRL

2

1

High-throughput

0.571

High

396760

SLX4
Structure-specific endonuclease subunit SLX4

2

4

High-throughput

0.571

High

396766

DOCK8
Dedicator of cytokinesis protein 8

2

4

High-throughput

0.571

High

396671

TAU
Microtubule-associated protein tau

2

12

Small-scale

0.552

High

396712

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.541

High

396730

U119A
Protein unc-119 homolog A

1

1

High-throughput

0.541

High

125957

UPK1A
Uroplakin-1a

1

8

High-throughput

0.536

High

198369

KLK10
Kallikrein-10

1

8

High-throughput

0.536

High

209304

TSN6
Tetraspanin-6

1

5

High-throughput

0.536

High

274900

RENR
Renin receptor

1

4

High-throughput

0.536

High

329069

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

3

High-throughput

0.536

High

396677

AATC
Aspartate aminotransferase, cytoplasmic

1

5

High-throughput

0.536

High

396680

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

10

High-throughput

0.536

High

396690

CCR1
C-C chemokine receptor type 1

1

6

High-throughput

0.536

High

396694

RYK
Tyrosine-protein kinase RYK

1

7

High-throughput

0.536

High

396695

CNR2
Cannabinoid receptor 2

1

1

Small-scale

0.536

High

396707

GSK3B
Glycogen synthase kinase-3 beta

1

5

High-throughput

0.536

High

396710

DSCR6
Protein ripply3

1

7

High-throughput

0.536

High

396713

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.536

High

396715

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

7

High-throughput

0.536

High

396723

GABPA
GA-binding protein alpha chain

1

7

High-throughput

0.536

High

396744

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.536

High

396756

DPH6
Diphthine--ammonia ligase

1

1

High-throughput

0.536

High

396757

APTX
Aprataxin

1

3

High-throughput

0.536

High

396765

FNDC5
Fibronectin type III domain-containing protein 5

1

7

High-throughput

0.536

High

396770

RHBL4
Rhomboid-related protein 4

1

5

High-throughput

0.536

High

396773

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

4

High-throughput

0.536

High

396779

CSN5
COP9 signalosome complex subunit 5

1

5

High-throughput

0.536

High

396790

EPAS1
Endothelial PAS domain-containing protein 1

1

5

High-throughput

0.536

High

396796

MMTA2
Multiple myeloma tumor-associated protein 2

1

4

High-throughput

0.536

High

396808

KMT5A
N-lysine methyltransferase KMT5A

1

10

High-throughput

0.536

High

396818

PHF11
PHD finger protein 11

1

10

High-throughput

0.536

High

396826

SSUH2
Protein SSUH2 homolog

1

3

High-throughput

0.536

High

396681

NCF2
Neutrophil cytosol factor 2

1

8

Small-scale

0.527

High

233920

GDF9
Growth/differentiation factor 9

1

0

High-throughput

0.518

High

393763

SCG1
Secretogranin-1

1

0

High-throughput

0.518

High

396736

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.518

High

396791

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.518

High

229914

NUAK1
NUAK family SNF1-like kinase 1

1

3

High-throughput

0.515

High

273342

PPM1B
Protein phosphatase 1B

1

2

High-throughput

0.515

High

396724

DMWD
Dystrophia myotonica WD repeat-containing protein

1

2

High-throughput

0.515

High

396743

USF2
Upstream stimulatory factor 2

1

11

High-throughput

0.515

High

396747

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

5

High-throughput

0.515

High

396806

MOB1A
MOB kinase activator 1A

1

2

High-throughput

0.515

High

396669

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

396769

MIPT3
TRAF3-interacting protein 1

1

0

Small-scale

0.513

High

393909

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

396667

TBB5
Tubulin beta chain

1

1

Small-scale

0.501

High

396691

NAC1
Sodium/calcium exchanger 1

1

17

Small-scale

0.501

High

396711

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

Small-scale

0.501

High

396755

TBA1A
Tubulin alpha-1A chain

1

4

Small-scale

0.501

High

396768

TRPM4
Transient receptor potential cation channel subfamily M member 4

1

12

Small-scale

0.501

High

396668

MET
Hepatocyte growth factor receptor

1

8

High-throughput

0.500

High

303627

OR2A4
Olfactory receptor 2A4

1

6

High-throughput

0.489

High

396705

PTSS1
Phosphatidylserine synthase 1

1

7

High-throughput

0.489

High

396746

CR021
UPF0711 protein C18orf21

1

5

High-throughput

0.489

High

396782

PIGT
GPI transamidase component PIG-T

1

3

High-throughput

0.489

High

396783

SARAF
Store-operated calcium entry-associated regulatory factor

1

3

High-throughput

0.489

High

396785

PF21B
PHD finger protein 21B

1

16

High-throughput

0.489

High

396793

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

4

High-throughput

0.489

High

396795

SH23A
SH2 domain-containing protein 3A

1

11

High-throughput

0.489

High

396809

ST7
Suppressor of tumorigenicity 7 protein

1

4

High-throughput

0.489

High

396700

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

396697

NOS2
Nitric oxide synthase, inducible

1

1

Small-scale

0.484

High

396672

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.480

High

171279

EPHB6
Ephrin type-B receptor 6

1

2

High-throughput

0.479

High

226249

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

231960

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.479

High

282473

RNF8
E3 ubiquitin-protein ligase RNF8

1

11

High-throughput

0.479

High

302776

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

324161

BAG3
BAG family molecular chaperone regulator 3

1

5

High-throughput

0.479

High

329230

AGR2
Anterior gradient protein 2 homolog

1

4

Small-scale

0.479

High

345040

CYTA
Cystatin-A

1

2

High-throughput

0.479

High

345674

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.479

High

349798

RASK
GTPase KRas

1

3

High-throughput

0.479

High

364636

TRFL
Lactotransferrin

1

1

High-throughput

0.479

High

373505

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

9

High-throughput

0.479

High

377001

GCR
Glucocorticoid receptor

1

16

Small-scale

0.479

High

396670

H2A1
Histone H2A type 1

1

2

High-throughput

0.479

High

396674

INSRR
Insulin receptor-related protein

1

9

High-throughput

0.479

High

396675

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

Small-scale

0.479

High

396682

SPR2E
Small proline-rich protein 2E

1

1

High-throughput

0.479

High

396684

ZA2G
Zinc-alpha-2-glycoprotein

1

1

High-throughput

0.479

High

396685

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

5

High-throughput

0.479

High

396687

SPB3
Serpin B3

1

7

High-throughput

0.479

High

396689

CASPE
Caspase-14

1

4

High-throughput

0.479

High

396692

ELF1
ETS-related transcription factor Elf-1

1

7

High-throughput

0.479

High

396693

MCM5
DNA replication licensing factor MCM5

1

8

High-throughput

0.479

High

396698

MERL
Merlin

1

5

High-throughput

0.479

High

396701

CEAM3
Carcinoembryonic antigen-related cell adhesion molecule 3

1

1

Small-scale

0.479

High

396702

VHL
von Hippel-Lindau disease tumor suppressor

1

3

High-throughput

0.479

High

396703

LEG7
Galectin-7

1

2

High-throughput

0.479

High

396704

SPB4
Serpin B4

1

7

High-throughput

0.479

High

396706

MCM2
DNA replication licensing factor MCM2

1

8

High-throughput

0.479

High

396709

TERF1
Telomeric repeat-binding factor 1

1

2

High-throughput

0.479

High

396714

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

Small-scale

0.479

High

396718

HSF1
Heat shock factor protein 1

1

5

High-throughput

0.479

High

396719

FABP5
Fatty acid-binding protein 5

1

2

High-throughput

0.479

High

396720

TFAP4
Transcription factor AP-4

1

1

Small-scale

0.479

High

396722

K1C17
Keratin, type I cytoskeletal 17

1

3

High-throughput

0.479

High

396727

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

8

High-throughput

0.479

High

396728

NFX1
Transcriptional repressor NF-X1

1

2

High-throughput

0.479

High

396729

ERCC8
DNA excision repair protein ERCC-8

1

4

Small-scale

0.479

High

396731

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

396732

CUL2
Cullin-2

1

8

High-throughput

0.479

High

396733

DX39B
Spliceosome RNA helicase DDX39B

1

9

High-throughput

0.479

High

396734

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

13

High-throughput

0.479

High

396737

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

8

High-throughput

0.479

High

396738

TNIP1
TNFAIP3-interacting protein 1

1

19

High-throughput

0.479

High

396741

TERF2
Telomeric repeat-binding factor 2

1

2

High-throughput

0.479

High

396742

IKBB
NF-kappa-B inhibitor beta

1

2

High-throughput

0.479

High

396752

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

396753

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

396754

PAXI1
PAX-interacting protein 1

1

5

High-throughput

0.479

High

396758

ZN598
E3 ubiquitin-protein ligase ZNF598

1

4

High-throughput

0.479

High

396759

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

9

Small-scale

0.479

High

396763

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

Small-scale

0.479

High

396767

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

396771

TP4AP
Short transient receptor potential channel 4-associated protein

1

2

High-throughput

0.479

High

396777

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.479

High

396778

HDAC2
Histone deacetylase 2

1

6

High-throughput

0.479

High

396781

FBXW7
F-box/WD repeat-containing protein 7

1

6

High-throughput

0.479

High

396786

AURKB
Aurora kinase B

1

9

High-throughput

0.479

High

396789

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

6

High-throughput

0.479

High

396799

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

396800

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.479

High

396805

DOCK5
Dedicator of cytokinesis protein 5

1

4

High-throughput

0.479

High

396807

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

5

High-throughput

0.479

High

396810

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

396811

TMPS4
Transmembrane protease serine 4

1

3

High-throughput

0.479

High

396815

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

2

High-throughput

0.479

High

396817

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

396819

MBD1
Methyl-CpG-binding domain protein 1

1

4

Small-scale

0.479

High

396820

RALY
RNA-binding protein Raly

1

2

High-throughput

0.479

High

396822

RL26L
Ribosomal protein uL24-like

1

1

High-throughput

0.479

High

396823

MOK
MAPK/MAK/MRK overlapping kinase

1

10

Small-scale

0.479

High

396825

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

11

Small-scale

0.479

High

396827

RNF11
RING finger protein 11

1

5

Small-scale

0.479

High

396828

RL36
Large ribosomal subunit protein eL36

1

1

High-throughput

0.479

High

396829

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

396830

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

Small-scale

0.479

High

396831

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.479

High

396832

ASB3
Ankyrin repeat and SOCS box protein 3

1

4

High-throughput

0.479

High

396678

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.458

High

396708

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

396725

RBBP4
Histone-binding protein RBBP4

1

0

High-throughput

0.458

High

396735

BECN1
Beclin-1

1

0

Small-scale

0.458

High

396739

ELOC
Elongin-C

1

0

High-throughput

0.458

High

396740

ELOB
Elongin-B

1

0

High-throughput

0.458

High

396774

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.458

High

396780

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

Small-scale

0.458

High

396784

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.458

High

396676

ZNF16
Zinc finger protein 16

1

2

Small-scale

0.457

High

396716

TBA4A
Tubulin alpha-4A chain

1

4

High-throughput

0.457

High

396751

RIF1
Telomere-associated protein RIF1

1

1

High-throughput

0.457

High

396802

KLC2
Kinesin light chain 2

1

10

High-throughput

0.457

High

396804

RAB17
Ras-related protein Rab-17

1

3

High-throughput

0.457

High

396696

CTNB1
Catenin beta-1

1

7

High-throughput

0.445

High

396748

ODFP2
Outer dense fiber protein 2

1

18

High-throughput

0.445

High

396749

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

396762

CD177
CD177 antigen

1

1

Small-scale

0.445

High

396772

CE192
Centrosomal protein of 192 kDa

1

4

High-throughput

0.445

High

396803

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

14

High-throughput

0.445

High

396699

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

396775

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.437

High

396776

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

3

High-throughput

0.437

High

396788

LMTK3
Serine/threonine-protein kinase LMTK3

1

7

High-throughput

0.437

High

396801

DDX24
ATP-dependent RNA helicase DDX24

1

9

High-throughput

0.437

High

396813

POTE1
Protection of telomeres protein 1

1

1

High-throughput

0.437

High

396814

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

4

High-throughput

0.437

High

396761

S15A4
Solute carrier family 15 member 4

1

0

Small-scale

0.426

High

396787

IGS21
Immunoglobulin superfamily member 21

1

0

High-throughput

0.282

High

396821

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

396794

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.279

Low

396816

WRP73
WD repeat-containing protein WRAP73

1

0

High-throughput

0.279

Low

396750

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024