HitPredict

Interactor 1: ACVR1 (Q04771)
Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)
Gene: ACVR1

Interactor 2: MRAP2 (Q96G30)
Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2)
Gene: MRAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 205
+	Hs
		738397 BMR1A_HUMAN (25-503): 1.29e-137: 409: 49.79		MRAP2_HUMAN (1-205): 1.45e-148: 412: 100.00
+	Hs
		738481 ACV1B_HUMAN (28-503): 2.21e-124: 374: 49.79		MRAP2_HUMAN (1-205): 1.45e-148: 412: 100.00
+	Hs
		1046381 BMPR2_HUMAN (49-507): 3.21e-105: 339: 30.66		MRAP2_HUMAN (1-205): 1.45e-148: 412: 100.00
+	Hs
		1044934 AVR2B_HUMAN (46-509): 4.4e-107: 330: 29.46		MRAP2_HUMAN (1-205): 1.45e-148: 412: 100.00
+	Hs
		646058 AVR2A_HUMAN (52-508): 7.82e-102: 316: 29.33		MRAP2_HUMAN (1-205): 1.45e-148: 412: 100.00