Protein: H2B1J
Histone H2B type 1-J (Histone H2B.1) (Histone H2B.r) (H2B/r)

Gene: H2B1J, H2BC11
Organism: Homo sapiens
Interactions: 180
UniProt ID: P06899

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0001530 - lipopolysaccharide binding
GO:0002227 - innate immune response in mucosa
GO:0003677 - DNA binding
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

418783

H2A1B
Histone H2A type 1-B/E

6

20

Small-scale

0.939

High

449698

H4
Histone H4

5

20

High-throughput

0.906

High

449673

H2AX
Histone H2AX

4

20

High-throughput

0.886

High

449770

H2B1A
Histone H2B type 1-A

4

20

High-throughput

0.886

High

449664

H2A1
Histone H2A type 1

3

20

High-throughput

0.847

High

449735

H2A2A
Histone H2A type 2-A

3

20

High-throughput

0.847

High

449699

H2B1C
Histone H2B type 1-C/E/F/G/I

3

20

High-throughput

0.827

High

449702

H31
Histone H3.1

3

20

High-throughput

0.827

High

449709

MDM2
E3 ubiquitin-protein ligase Mdm2

2

4

High-throughput

0.811

High

256739

H2B1K
Histone H2B type 1-K

2

20

High-throughput

0.754

High

449667

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

20

High-throughput

0.754

High

449678

H2A1D
Histone H2A type 1-D

2

20

High-throughput

0.754

High

449683

H2B1B
Histone H2B type 1-B

2

20

High-throughput

0.754

High

449708

H33
Histone H3.3

2

20

High-throughput

0.754

High

449740

H32
Histone H3.2

2

20

High-throughput

0.754

High

449768

H2B1H
Histone H2B type 1-H

2

20

High-throughput

0.754

High

449780

H2B1L
Histone H2B type 1-L

2

20

High-throughput

0.754

High

449707

CBX1
Chromobox protein homolog 1

1

20

High-throughput

0.691

High

449712

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.691

High

449800

H2AW
Core histone macro-H2A.2

1

20

High-throughput

0.691

High

449803

DAXX
Death domain-associated protein 6

1

3

High-throughput

0.691

High

449760

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

0

Small-scale

0.687

High

449746

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

3

20

Small-scale

0.667

High

387688

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

2

16

High-throughput

0.628

High

387776

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

16

High-throughput

0.628

High

387938

FIBG
Fibrinogen gamma chain

2

16

High-throughput

0.628

High

449703

HBB
Hemoglobin subunit beta

2

1

High-throughput

0.628

High

186983

PPM1G
Protein phosphatase 1G

2

11

High-throughput

0.621

High

449661

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.618

High

449663

H2AZ
Histone H2A.Z

1

20

High-throughput

0.618

High

449666

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

449679

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.618

High

449690

MCM2
DNA replication licensing factor MCM2

1

20

High-throughput

0.618

High

449693

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.618

High

449695

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.618

High

449700

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

20

High-throughput

0.618

High

449701

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

20

High-throughput

0.618

High

449715

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.618

High

449722

H31T
Histone H3.1t

1

20

High-throughput

0.618

High

449723

H2A2C
Histone H2A type 2-C

1

20

High-throughput

0.618

High

449724

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.618

High

449730

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.618

High

449734

RN123
E3 ubiquitin-protein ligase RNF123

1

7

High-throughput

0.618

High

449736

H3C
Histone H3.3C

1

20

High-throughput

0.618

High

449741

H2AV
Histone H2A.V

1

20

High-throughput

0.618

High

449744

H2A3
Histone H2A type 3

1

20

High-throughput

0.618

High

449747

H2A2B
Histone H2A type 2-B

1

20

High-throughput

0.618

High

449752

H2B3B
Histone H2B type 3-B

1

20

High-throughput

0.618

High

449764

H1X
Histone H1.10

1

4

High-throughput

0.618

High

449767

H2A1C
Histone H2A type 1-C

1

20

High-throughput

0.618

High

449773

H2A1H
Histone H2A type 1-H

1

20

High-throughput

0.618

High

449774

NP1L5
Nucleosome assembly protein 1-like 5

1

16

High-throughput

0.618

High

449775

H2A1A
Histone H2A type 1-A

1

20

High-throughput

0.618

High

449776

NP1L4
Nucleosome assembly protein 1-like 4

1

20

High-throughput

0.618

High

449777

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.618

High

449778

H2A1J
Histone H2A type 1-J

1

20

High-throughput

0.618

High

449779

H2B1M
Histone H2B type 1-M

1

20

High-throughput

0.618

High

449783

H2AJ
Histone H2A.J

1

20

High-throughput

0.618

High

449791

WDR76
WD repeat-containing protein 76

1

18

High-throughput

0.618

High

449795

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

9

High-throughput

0.618

High

449804

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.618

High

449809

SP16H
FACT complex subunit SPT16

1

8

High-throughput

0.618

High

137410

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

2

20

High-throughput

0.611

High

449668

TAU
Microtubule-associated protein tau

2

20

High-throughput

0.601

High

426422

HMGN2
Non-histone chromosomal protein HMG-17

2

20

High-throughput

0.584

High

449669

TOP2A
DNA topoisomerase 2-alpha

2

15

High-throughput

0.584

High

449794

ANLN
Anillin

2

3

High-throughput

0.584

High

436579

KPCB
Protein kinase C beta type

2

20

High-throughput

0.571

High

449691

KS6A3
Ribosomal protein S6 kinase alpha-3

2

20

High-throughput

0.571

High

449769

IGSF8
Immunoglobulin superfamily member 8

1

20

High-throughput

0.553

High

224927

TLX3
T-cell leukemia homeobox protein 3

1

2

High-throughput

0.541

High

352292

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.536

High

388904

FINC
Fibronectin

1

20

High-throughput

0.536

High

449662

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.536

High

449674

CREB1
Cyclic AMP-responsive element-binding protein 1

1

2

High-throughput

0.536

High

449676

VCAM1
Vascular cell adhesion protein 1

1

11

High-throughput

0.536

High

449704

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.536

High

449717

KRR1
KRR1 small subunit processome component homolog

1

2

High-throughput

0.536

High

449755

PAF1
RNA polymerase II-associated factor 1 homolog

1

2

High-throughput

0.536

High

449772

ZN514
Zinc finger protein 514

1

3

High-throughput

0.536

High

449737

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

7

High-throughput

0.508

High

449802

CFDP1
Craniofacial development protein 1

1

5

High-throughput

0.489

High

137916

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

13

High-throughput

0.479

High

156849

CTRO
Citron Rho-interacting kinase

1

17

High-throughput

0.479

High

176126

PER2
Period circadian protein homolog 2

1

1

Small-scale

0.479

High

222640

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.479

High

247605

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

259314

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.479

High

297405

PIAS1
E3 SUMO-protein ligase PIAS1

1

5

High-throughput

0.479

High

323104

TRI37
E3 ubiquitin-protein ligase TRIM37

1

18

High-throughput

0.479

High

324418

HEXI1
Protein HEXIM1

1

14

High-throughput

0.479

High

330574

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

334490

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

4

Small-scale

0.479

High

385367

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

8

High-throughput

0.479

High

424334

HMGN1
Non-histone chromosomal protein HMG-14

1

8

High-throughput

0.479

High

427774

ICAM1
Intercellular adhesion molecule 1

1

20

High-throughput

0.479

High

449665

H2AB2
Histone H2A-Bbd type 2/3

1

20

High-throughput

0.479

High

449670

ADT3
ADP/ATP translocase 3

1

5

High-throughput

0.479

High

449672

HCLS1
Hematopoietic lineage cell-specific protein

1

20

High-throughput

0.479

High

449675

HMGA1
High mobility group protein HMG-I/HMG-Y

1

15

High-throughput

0.479

High

449677

BTF3
Transcription factor BTF3

1

11

High-throughput

0.479

High

449680

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

11

High-throughput

0.479

High

449681

AKT1
RAC-alpha serine/threonine-protein kinase

1

20

High-throughput

0.479

High

449682

AKT2
RAC-beta serine/threonine-protein kinase

1

20

High-throughput

0.479

High

449684

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.479

High

449685

CYLC1
Cylicin-1

1

20

High-throughput

0.479

High

449686

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

3

High-throughput

0.479

High

449688

MAP1B
Microtubule-associated protein 1B

1

20

High-throughput

0.479

High

449689

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

7

High-throughput

0.479

High

449696

CD81
CD81 antigen

1

11

High-throughput

0.479

High

449697

WDR5
WD repeat-containing protein 5

1

7

High-throughput

0.479

High

449705

RED1
Double-stranded RNA-specific editase 1

1

14

High-throughput

0.479

High

449706

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

2

High-throughput

0.479

High

449710

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

9

High-throughput

0.479

High

449711

KIF23
Kinesin-like protein KIF23

1

20

High-throughput

0.479

High

449713

ACACA
Acetyl-CoA carboxylase 1

1

1

High-throughput

0.479

High

449714

REST
RE1-silencing transcription factor

1

7

High-throughput

0.479

High

449718

CKAP5
Cytoskeleton-associated protein 5

1

8

High-throughput

0.479

High

449719

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

449720

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.479

High

449721

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

1

14

High-throughput

0.479

High

449726

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

449727

PDCD4
Programmed cell death protein 4

1

8

High-throughput

0.479

High

449728

SGO2
Shugoshin 2

1

2

High-throughput

0.479

High

449731

TEX35
Testis-expressed protein 35

1

12

High-throughput

0.479

High

449732

SMBT2
Scm-like with four MBT domains protein 2

1

20

High-throughput

0.479

High

449743

MEPCE
7SK snRNA methylphosphate capping enzyme

1

14

High-throughput

0.479

High

449745

DPPA2
Developmental pluripotency-associated protein 2

1

10

High-throughput

0.479

High

449748

APLF
Aprataxin and PNK-like factor

1

1

High-throughput

0.479

High

449749

PARP9
Protein mono-ADP-ribosyltransferase PARP9

1

20

Small-scale

0.479

High

449751

RBIS
Ribosomal biogenesis factor

1

2

High-throughput

0.479

High

449757

SERB1
SERPINE1 mRNA-binding protein 1

1

12

High-throughput

0.479

High

449759

RIN3
Ras and Rab interactor 3

1

19

High-throughput

0.479

High

449763

ELYS
Protein ELYS

1

20

High-throughput

0.479

High

449765

TOPB1
DNA topoisomerase 2-binding protein 1

1

10

High-throughput

0.479

High

449766

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

449781

SPI2B
Spindlin-2B

1

1

High-throughput

0.479

High

449782

RIOK1
Serine/threonine-protein kinase RIO1

1

12

High-throughput

0.479

High

449784

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

20

High-throughput

0.479

High

449785

FACD2
Fanconi anemia group D2 protein

1

9

High-throughput

0.479

High

449786

ACE2
Angiotensin-converting enzyme 2

1

4

High-throughput

0.479

High

449787

RNF38
E3 ubiquitin-protein ligase RNF38

1

2

Small-scale

0.479

High

449788

ADNP
Activity-dependent neuroprotector homeobox protein

1

2

High-throughput

0.479

High

449789

CHM4B
Charged multivesicular body protein 4b

1

9

High-throughput

0.479

High

449790

ECT2
Protein ECT2

1

4

High-throughput

0.479

High

449793

PRD16
Histone-lysine N-methyltransferase PRDM16

1

3

High-throughput

0.479

High

449796

DUOX2
Dual oxidase 2

1

12

High-throughput

0.479

High

449797

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

20

High-throughput

0.479

High

449798

RNF12
E3 ubiquitin-protein ligase RLIM

1

4

High-throughput

0.479

High

449801

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

20

High-throughput

0.479

High

449805

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

1

High-throughput

0.479

High

449806

SMC3
Structural maintenance of chromosomes protein 3

1

12

High-throughput

0.479

High

449807

TENN
Tenascin-N

1

20

High-throughput

0.479

High

449808

LOXL2
Lysyl oxidase homolog 2

1

3

High-throughput

0.479

High

326131

REC8
Meiotic recombination protein REC8 homolog

1

0

High-throughput

0.458

High

449671

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

449687

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.458

High

449733

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

449692

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.445

High

449742

H1FNT
Testis-specific H1 histone

1

5

High-throughput

0.445

High

449750

ASPM
Abnormal spindle-like microcephaly-associated protein

1

6

Small-scale

0.445

High

449792

ARP5
Actin-related protein 5

1

13

Small-scale

0.445

High

449729

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

3

High-throughput

0.439

High

125927

SMAP
Small acidic protein

1

4

High-throughput

0.437

High

317973

TOM70
Mitochondrial import receptor subunit TOM70

1

10

High-throughput

0.437

High

449694

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

9

High-throughput

0.437

High

449716

CD5R2
Cyclin-dependent kinase 5 activator 2

1

12

High-throughput

0.437

High

449725

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

20

High-throughput

0.437

High

449738

ZN474
Zinc finger protein 474

1

10

High-throughput

0.437

High

449739

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

449753

RHG24
Rho GTPase-activating protein 24

1

15

High-throughput

0.437

High

449756

FA47B
Protein FAM47B

1

20

High-throughput

0.437

High

449761

DNJB3
DnaJ homolog subfamily B member 3

1

3

High-throughput

0.437

High

449762

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

3

High-throughput

0.437

High

449799

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

4

High-throughput

0.437

High

449810

PCLO
Protein piccolo

1

20

High-throughput

0.437

High

449771

CMBL
Carboxymethylenebutenolidase homolog

1

0

High-throughput

0.426

High

449754

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

449758

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025