HitPredict

Interactor 1: SOX8 (Q04886)
Transcription factor SOX-8
Gene: SOX8

Interactor 2: HXC4 (Q08624)
Homeobox protein Hox-C4 (Homeobox protein Hox-3.5)
Gene: Hoxc4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	16582099
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 464 Mm			1 264
+	Dm
		950019 PANG2_DROME (41-447): 3.17e-42: 162: 15.22		UBX_DROME (19-217): 5.81e-32: 122: 27.54
+	Hs
		174010 SOX6_HUMAN (32-302): 2.1e-39: 153: 24.13		SHOX_HUMAN (138-218): 8.2e-34: 125: 32.10
+	Hs
		678805 CIC_HUMAN (30-341): 1.13e-35: 143: 18.89		HXA10_HUMAN (15-226): 3.78e-36: 134: 29.52
+	Hs
		595628 CIC_HUMAN (30-341): 1.13e-35: 143: 18.89		HXA5_HUMAN (44-228): 1.68e-34: 126: 43.55
+	Hs
		595639 SOX17_HUMAN (96-322): 1.43e-37: 143: 34.03		HXA5_HUMAN (44-228): 1.68e-34: 126: 43.55
+	Dm
		950090 Q9VUD3_DROME (74-213): 2.71e-37: 145: 40.41		UBX_DROME (19-217): 5.81e-32: 122: 27.54
+	Hs
		882171 SOX13_HUMAN (94-175): 1.34e-34: 138: 47.56		GSC_HUMAN (10-251): 2.5e-34: 126: 15.64
+	Mm
		192288 SOX15_MOUSE (99-203): 5.4e-38: 140: 52.29		ALX4_MOUSE (74-262): 5.44e-31: 120: 20.11
+	Dm
		115538 M9PFG6_DROME (88-175): 2.19e-35: 137: 54.55		UBX_DROME (19-217): 5.81e-32: 122: 27.54
+	Dm
		668264 PANG2_DROME (41-447): 3.17e-42: 162: 15.22		ABDA_DROME (152-216): 3.52e-21: 94.4: 75.39
+	Hs
		727714 SOX5_HUMAN (80-176): 1.1e-31: 130: 42.27		GSC_HUMAN (10-251): 2.5e-34: 126: 15.64
+	Hs
		174009 SOX5_HUMAN (80-176): 1.1e-31: 130: 42.27		SHOX_HUMAN (138-218): 8.2e-34: 125: 32.10
+	Mm
		446925 Q60I23_MOUSE (62-392): 1.47e-28: 116: 25.98		HXA5_MOUSE (44-228): 1.79e-35: 129: 44.62
+	Hs
		595592 SOX2_HUMAN (68-392): 1.14e-28: 117: 25.85		HXA5_HUMAN (44-228): 1.68e-34: 126: 43.55
+	Dm
		668309 Q9VUD3_DROME (74-213): 2.71e-37: 145: 40.41		ABDA_DROME (152-216): 3.52e-21: 94.4: 75.39
+	Hs
		818455 SOX2_HUMAN (68-392): 1.14e-28: 117: 25.85		ALX4_HUMAN (74-262): 4.32e-31: 120: 19.05
+	Hs
		882164 HM20B_HUMAN (60-173): 1.39e-26: 111: 18.42		GSC_HUMAN (10-251): 2.5e-34: 126: 15.64
+	Mm
		192289 SOX2_MOUSE (62-392): 2.99e-27: 113: 25.68		ALX4_MOUSE (74-262): 5.44e-31: 120: 20.11
+	Dm
		115535 M9PFG6_DROME (88-175): 2.19e-35: 137: 54.55		ABDA_DROME (152-216): 3.52e-21: 94.4: 75.39
+	Dm
		668228 SOX15_DROME (72-290): 6.4e-31: 128: 31.51		ABDA_DROME (152-216): 3.52e-21: 94.4: 75.39