HitPredict

Interactor 1: CYK2 (Q05080)
Cytokinesis protein 2 (Homolog of CDC15 protein 1)
Gene: HOF1

Interactor 2: LAS17 (Q12446)
Proline-rich protein LAS17
Gene: LAS17

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	11743162, 19841731, 19272406
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030041 - actin filament polymerization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 669 Sc			1 633
+	Sc
		748826 RGD1_YEAST (12-445): 3.22e-74: 253: 16.85		LAS17_YEAST (1-633): 8.22e-51: 188: 100.00
+	Sc
		755687 BZZ1_YEAST (15-663): 2.55e-55: 201: 13.86		LAS17_YEAST (1-633): 8.22e-51: 188: 100.00
+	Hs
		126938 FBP1L_HUMAN (1-664): 2.49e-63: 222: 14.58		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Rn
		94090 FNBP1_RAT (1-664): 1.07e-59: 213: 13.63		F1LSG0_RAT (3-154): 4.14e-46: 172: 28.95
+	Hs
		126956 FNBP1_HUMAN (1-664): 1e-60: 215: 13.31		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Hs
		126889 FCSD2_HUMAN (20-666): 3.09e-55: 202: 12.30		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Mm
		936466 Q0VBR8_MOUSE (3-276): 3.49e-63: 217: 20.92		WASP_MOUSE (3-386): 3.86e-37: 147: 18.37
+	Dm
		1361429 Q9VZD7_DROME (1-664): 1.27e-55: 202: 11.76		Q9VAT0_DROME (3-215): 8.21e-40: 154: 18.18
+	Dm
		112684 M9NE16_DROME (1-664): 1.01e-53: 196: 11.76		Q9VAT0_DROME (3-215): 8.21e-40: 154: 18.18
+	Hs
		242926 GAS7_HUMAN (3-276): 5.2e-68: 232: 21.63		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Hs
		126935 CIP4_HUMAN (1-498): 2.9e-49: 183: 13.26		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Dm
		1361432 NWK_DROME (25-664): 4.68e-50: 190: 10.78		Q9VAT0_DROME (3-215): 8.21e-40: 154: 18.18
+	Hs
		790685 FNBP1_HUMAN (1-664): 1e-60: 215: 13.31		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Hs
		297961 FCSD2_HUMAN (20-666): 3.09e-55: 202: 12.30		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Hs
		790675 CIP4_HUMAN (1-498): 2.9e-49: 183: 13.26		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Rn
		94091 ITSN1_RAT (25-669): 1.3e-18: 93.1: 9.29		F1LSG0_RAT (3-154): 4.14e-46: 172: 28.95
+	Hs
		126969 PACN2_HUMAN (173-666): 1.08e-18: 91.5: 8.49		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Mm
		101457 CIP4_MOUSE (1-479): 1.83e-50: 187: 12.75		F8VPR5_MOUSE (175-602): 5.56e-09: 61.7: 12.93
+	Hs
		790694 PACN2_HUMAN (173-666): 1.08e-18: 91.5: 8.49		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Hs
		203262 PACN2_HUMAN (173-666): 1.08e-18: 91.5: 8.49		SYNJ1_HUMAN (89-538): 6.62e-22: 103: 12.06