HitPredict

Interactor 1: UBE3A (Q05086)
Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)
Gene: UBE3A

Interactor 2: E41L3 (Q9Y2J2)
Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]
Gene: EPB41L3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29511261
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 875 Hs			1 1087
+	Hs
		640238 UBE3A_HUMAN (1-875): 0: 1058: 100.00		PTN3_HUMAN (90-701): 3.39e-122: 399: 23.67
+	Hs
		1336123 SMUF1_HUMAN (405-872): 1.32e-175: 528: 27.04		E41L3_HUMAN (1-1087): 0: 752: 100.00
+	Hs
		204654 UBE3A_HUMAN (1-875): 0: 1058: 100.00		E41L2_HUMAN (583-1087): 1.39e-44: 177: 32.64
+	Hs
		546967 NEDD4_HUMAN (46-873): 0: 622: 21.49		EZRI_HUMAN (106-636): 1.38e-120: 384: 22.28
+	Hs
		125485 WWP2_HUMAN (291-873): 0: 589: 24.72		PTN14_HUMAN (91-1077): 1.78e-119: 398: 15.41
+	Hs
		1076918 WWP1_HUMAN (185-873): 0: 560: 22.22		PTN14_HUMAN (91-1077): 1.78e-119: 398: 15.41
+	Hs
		1192278 HUWE1_HUMAN (523-874): 5.96e-53: 203: 33.97		E41L3_HUMAN (1-1087): 0: 752: 100.00
+	Hs
		1087931 WWP1_HUMAN (185-873): 0: 560: 22.22		PTN21_HUMAN (91-1043): 1.1e-117: 393: 18.61
+	Hs
		547209 WWP1_HUMAN (185-873): 0: 560: 22.22		EZRI_HUMAN (106-636): 1.38e-120: 384: 22.28
+	Mm
		1186496 HUWE1_MOUSE (523-874): 7.59e-53: 203: 33.97		E41L3_MOUSE (525-1087): 7.78e-64: 236: 60.60