Interactor 1: DCE2 (Q05329)
Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform)
Gene: GAD2

Interactor 2: DCE1 (Q99259)
Glutamate decarboxylase 1 (EC 4.1.1.15) (67 kDa glutamic acid decarboxylase) (GAD-67) (Glutamate decarboxylase 67 kDa isoform)
Gene: GAD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 7836456
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pyridoxal_deC~Pyridoxal_deC
Common GO terms GO:0004351 - glutamate decarboxylase activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006540 - glutamate decarboxylation to succinate
GO:0007268 - chemical synaptic transmission
and 5 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 585
Hs

1 594
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs
+ At
+ Ce
+ Ce
+ Hs
+ At
+ Ec
+ Sc
+ Hs
+ Ec
+ Ec
+ Ec
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024