HitPredict

Interactor 1: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Interactor 2: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 602
+	Hs
		983951 KPCZ_HUMAN (1-592): 0: 688: 100.00		MRCKB_HUMAN (92-509): 4.22e-15: 81.1: 13.21
+	Hs
		117013 SGK1_HUMAN (199-583): 7.41e-144: 424: 38.36		MYH14_HUMAN (127-597): 5.01e-26: 116: 13.49
+	Hs
		681696 AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39		MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78
+	Hs
		568568 KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06		MYH10_HUMAN (175-601): 2.98e-20: 98: 10.72
+	Hs
		116964 SGK1_HUMAN (199-583): 7.41e-144: 424: 38.36		MYH1_HUMAN (51-518): 1.28e-15: 82.9: 10.32
+	Hs
		568567 KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06		MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78
+	Hs
		568720 KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06		CNTRL_HUMAN (127-595): 4.34e-09: 61.9: 13.20
+	Hs
		675140 KS6A3_HUMAN (168-539): 2.67e-105: 335: 20.47		CLIP1_HUMAN (135-600): 1.12e-09: 63.8: 15.06
+	Mm
		554927 KPCE_MOUSE (6-190): 3.27e-27: 118: 18.91		MYH7_MOUSE (45-602): 4.5e-19: 94.1: 11.25
+	Mm
		554901 KPCE_MOUSE (6-190): 3.27e-27: 118: 18.91		MYH6_MOUSE (50-601): 5.17e-19: 93.7: 10.80
+	Hs
		724784 KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02		MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78
+	Dm
		397193 KPC1_DROME (85-188): 6.16e-17: 86.5: 25.00		MYSN_DROME (4-602): 2.13e-21: 101: 10.36