HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: ITPR2 (Q14571)
Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)
Gene: ITPR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 2701
+	Hs
		724829 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		ITPR2_HUMAN (1-2701): 0: 4407: 100.00
+	Hs
		234216 PEPL_HUMAN (15-671): 2.36e-17: 89.5: 8.61		ITPR2_HUMAN (1-2701): 0: 4407: 100.00
+	Hs
		984585 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		ITPR1_HUMAN (1-2695): 0: 3987: 68.01
+	Hs
		984584 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		ITPR3_HUMAN (4-2687): 0: 3912: 64.48
+	Hs
		1056289 PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94		ITPR1_HUMAN (1-2695): 0: 3987: 68.01
+	Hs
		724830 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		ITPR3_HUMAN (4-2687): 0: 3912: 64.48
+	Hs
		234217 PEPL_HUMAN (15-671): 2.36e-17: 89.5: 8.61		ITPR3_HUMAN (4-2687): 0: 3912: 64.48
+	Hs
		148813 CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87		ITPR3_HUMAN (4-2687): 0: 3912: 64.48
+	Ce
		104565 G5EBY3_CAEEL (3-792): 1.41e-34: 144: 11.81		ITPR_CAEEL (9-2676): 0: 3221: 37.85
+	Ce
		522319 MYO2_CAEEL (82-710): 4.15e-26: 117: 10.79		ITPR_CAEEL (9-2676): 0: 3221: 37.85
+	Hs
		551717 DESP_HUMAN (13-640): 3.03e-22: 105: 14.35		RYR3_HUMAN (1734-2008): 1.95e-55: 218: 26.48
+	Mm
		93490 PLEC_MOUSE (5-781): 5.88e-19: 94.9: 9.56		RYR2_MOUSE (1746-2208): 6.15e-48: 193: 19.85
+	Hs
		551607 DESP_HUMAN (13-640): 3.03e-22: 105: 14.35		RYR1_HUMAN (1746-2208): 6.55e-44: 179: 21.35