HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: CING (Q9P2M7)
Cingulin
Gene: CGN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005886 - plasma membrane GO:0045296 - cadherin binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 1203
+	Hs
		1268105 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		CING_HUMAN (1-1203): 7.29e-107: 366: 100.00
+	Hs
		728523 MYH11_HUMAN (2-686): 1.62e-23: 109: 9.77		CING_HUMAN (1-1203): 7.29e-107: 366: 100.00
+	Xl
		1351510 CING_XENLA (2-691): 9.04e-26: 116: 10.65		CING_XENLA (116-1203): 2.93e-84: 303: 42.65
+	Rn
		361106 MYH6_RAT (1-792): 1.31e-29: 129: 10.29		MYH6_RAT (31-998): 9.92e-42: 169: 11.97
+	Hs
		724790 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		MYH9_HUMAN (724-1202): 1.4e-22: 107: 15.91
+	Hs
		528435 MYH4_HUMAN (1-788): 6.02e-31: 133: 10.45		MYH8_HUMAN (615-1202): 1.36e-29: 130: 15.99
+	Hs
		725095 MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63		MYH10_HUMAN (31-769): 7.74e-29: 127: 10.69
+	Hs
		522657 MYH4_HUMAN (1-788): 6.02e-31: 133: 10.45		MYH7_HUMAN (85-700): 7.96e-23: 108: 13.02
+	Hs
		724943 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		MYH9_HUMAN (724-1202): 1.4e-22: 107: 15.91
+	Hs
		502933 MYH4_HUMAN (1-788): 6.02e-31: 133: 10.45		MYH3_HUMAN (34-605): 9.9e-20: 98.3: 10.39
+	Hs
		724687 MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63		MYH9_HUMAN (724-1202): 1.4e-22: 107: 15.91
+	Hs
		1078856 ITSN1_HUMAN (235-636): 6.18e-27: 120: 21.34		MYH14_HUMAN (355-1179): 1.87e-21: 103: 24.08
+	Hs
		528432 MYH8_HUMAN (1-687): 6.45e-24: 110: 11.87		MYH13_HUMAN (633-1202): 4.08e-24: 112: 14.85
+	Hs
		725189 MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63		MYH14_HUMAN (355-1179): 1.87e-21: 103: 24.08
+	Hs
		725086 MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29		MYH9_HUMAN (724-1202): 1.4e-22: 107: 15.91
+	Hs
		725097 MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63		MYH11_HUMAN (68-623): 3.79e-20: 99.5: 8.63
+	Dm
		1303379 MYSN_DROME (2-660): 2.34e-25: 115: 10.46		MYSN_DROME (43-496): 4.47e-14: 79.8: 11.38
+	Dd
		445145 MYS2_DICDI (1-727): 4.18e-25: 114: 12.53		MYS2_DICDI (523-1180): 2.79e-12: 73.9: 19.88