Protein: CYC1
Cytochrome c isoform 1 (Iso-1-cytochrome c) (Cytochrome c aerobic isoform)

Gene: CYC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: P00044

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0006122 - mitochondrial electron transport, ubiquinol to cytochrome c
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
GO:0009055 - electron transfer activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

357680

CCPR
Cytochrome c peroxidase, mitochondrial

10

0

Small-scale

0.922

High

357695

ERV1
Mitochondrial FAD-linked sulfhydryl oxidase ERV1

2

1

Small-scale

0.639

High

357686

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

3

High-throughput

0.618

High

357711

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

3

High-throughput

0.618

High

357689

ADT2
ADP,ATP carrier protein 2

2

3

Small-scale

0.611

High

357713

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

4

High-throughput

0.584

High

357677

CYC1
Cytochrome c isoform 1

1

3

Small-scale

0.575

High

357684

CY1
Cytochrome c1, heme protein, mitochondrial

1

1

Small-scale

0.575

High

357685

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

2

Small-scale

0.550

High

357700

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

1

Small-scale

0.501

High

357706

SFB3
SED5-binding protein 3

1

1

High-throughput

0.494

High

357679

CYB2
L-lactate dehydrogenase

1

1

High-throughput

0.479

High

357682

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

1

High-throughput

0.479

High

357683

VDAC1
Non-selective voltage-gated ion channel 1

1

2

High-throughput

0.479

High

357687

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.479

High

357694

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

357698

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

357701

MCR1
NADH-cytochrome b5 reductase 2

1

1

High-throughput

0.479

High

357702

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

357705

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

357716

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

2

High-throughput

0.479

High

357719

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

357678

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.458

High

357681

ATP6
ATP synthase subunit a

1

0

Small-scale

0.458

High

357688

OM45
Mitochondrial outer membrane protein OM45

1

0

High-throughput

0.458

High

357691

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.458

High

357692

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.458

High

357697

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

0

High-throughput

0.458

High

357704

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.458

High

357709

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

357714

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

357715

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

357717

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

357693

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.457

High

357696

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

357710

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

357703

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

357690

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.249

Low

357699

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

357707

RPN10
26S proteasome regulatory subunit RPN10

1

0

Small-scale

0.249

Low

357708

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

357712

PDR11
ATP-dependent permease PDR11

1

0

High-throughput

0.249

Low

357718

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025