Interactor 1: PGH2 (Q05769)
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (Glucocorticoid-regulated inflammatory cyclooxygenase) (Gripghs) (Macrophage activation-associated marker protein P71/73) (PES-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2) (TIS10 protein)
Gene: Ptgs2

Interactor 2: PGH2 (Q05769)
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (Glucocorticoid-regulated inflammatory cyclooxygenase) (Gripghs) (Macrophage activation-associated marker protein P71/73) (PES-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2) (TIS10 protein)
Gene: Ptgs2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 21467029, 20463020
Identification Methods x-ray crystallography
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains An_peroxidase~An_peroxidase, An_peroxidase~EGF, EGF~EGF
Common GO terms GO:0001516 - prostaglandin biosynthetic process
GO:0001525 - angiogenesis
GO:0004601 - peroxidase activity
GO:0004666 - prostaglandin-endoperoxide synthase activity
GO:0005637 - nuclear inner membrane
and 72 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 604
Mm

1 604
+ Hs
+ Hs

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Last updated: 15 Jul 2024