Interactor 1: PGH2 (Q05769)
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (Glucocorticoid-regulated inflammatory cyclooxygenase) (Gripghs) (Macrophage activation-associated marker protein P71/73) (PES-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2) (TIS10 protein)
Gene: Ptgs2

Interactor 2: NOS1 (Q9Z0J4)
Nitric oxide synthase 1 (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Nitric oxide synthase, brain) (bNOS) (Peptidyl-cysteine S-nitrosylase NOS1)
Gene: NOS1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 18650379
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0008285 - negative regulation of cell population proliferation
GO:0019899 - enzyme binding
GO:0020037 - heme binding
GO:0032496 - response to lipopolysaccharide
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 604
Mm

1 1429
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024