HitPredict

Interactor 1: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Interactor 2: SLAF5 (Q9UIB8)
SLAM family member 5 (Cell surface antigen MAX.3) (Hly9-beta) (Leukocyte differentiation antigen CD84) (Signaling lymphocytic activation molecule 5) (CD antigen CD84)
Gene: CD84

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11689425
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032760 - positive regulation of tumor necrosis factor production
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 593 Hs			1 345
+	Hs
		986009 PTN11_HUMAN (1-593): 0: 581: 100.00		SLAF6_HUMAN (3-345): 1.05e-52: 178: 26.00
+	Hs
		985949 PTN11_HUMAN (1-593): 0: 581: 100.00		SLAF1_HUMAN (4-323): 1.91e-47: 165: 18.45
+	Hs
		986027 PTN11_HUMAN (1-593): 0: 581: 100.00		CD244_HUMAN (44-344): 4.75e-40: 146: 21.09
+	Hs
		986036 PTN11_HUMAN (1-593): 0: 581: 100.00		LY9_HUMAN (13-254): 6.07e-34: 133: 29.84
+	Hs
		532367 PTN11_HUMAN (1-593): 0: 581: 100.00		CEAM1_HUMAN (2-322): 5.8e-34: 132: 15.54
+	Hs
		665937 PTN6_HUMAN (6-593): 0: 531: 55.27		SLAF6_HUMAN (3-345): 1.05e-52: 178: 26.00
+	Mm
		682308 PTN11_MOUSE (1-593): 0: 580: 99.49		CEAM1_MOUSE (40-209): 3.02e-27: 113: 21.03
+	Hs
		665951 PTN6_HUMAN (6-593): 0: 531: 55.27		CD244_HUMAN (44-344): 4.75e-40: 146: 21.09
+	Hs
		532361 PTN6_HUMAN (6-593): 0: 531: 55.27		CEAM1_HUMAN (2-322): 5.8e-34: 132: 15.54
+	Hs
		68228 PTPRS_HUMAN (39-522): 8.52e-117: 384: 26.76		HECA2_HUMAN (1-206): 1.84e-46: 165: 21.62
+	Hs
		1031992 PTPRS_HUMAN (39-522): 8.52e-117: 384: 26.76		CEA21_HUMAN (8-285): 9.6e-47: 161: 17.53
+	Hs
		68222 PTPRF_HUMAN (33-522): 2.6e-112: 371: 25.85		HECA2_HUMAN (1-206): 1.84e-46: 165: 21.62
+	Hs
		489970 PTPRF_HUMAN (33-522): 2.6e-112: 371: 25.85		CEA21_HUMAN (8-285): 9.6e-47: 161: 17.53
+	Hs
		573657 PTN1_HUMAN (232-541): 4.38e-110: 338: 31.63		CXAR_HUMAN (1-328): 8.07e-54: 182: 13.28
+	Hs
		685236 PTPRS_HUMAN (39-522): 8.52e-117: 384: 26.76		CEAM8_HUMAN (35-243): 3.89e-19: 88.9: 13.68
+	Hs
		441196 PTPRC_HUMAN (33-579): 2.25e-85: 291: 18.29		SLAF1_HUMAN (4-323): 1.91e-47: 165: 18.45
+	Hs
		416911 PTPRC_HUMAN (33-579): 2.25e-85: 291: 18.29		CD2_HUMAN (2-342): 4.75e-43: 153: 18.57
+	Hs
		441208 PTPRC_HUMAN (33-579): 2.25e-85: 291: 18.29		CD244_HUMAN (44-344): 4.75e-40: 146: 21.09
+	Hs
		448945 PTPRK_HUMAN (36-524): 5.17e-72: 254: 18.94		CD48_HUMAN (21-239): 8.24e-47: 160: 18.67
+	Hs
		685244 PTPRK_HUMAN (36-524): 5.17e-72: 254: 18.94		CEAM8_HUMAN (35-243): 3.89e-19: 88.9: 13.68