Interactor 1: DCPS (Q06151)
m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Hint-related 7meGMP-directed hydrolase 1) (Protein Dcs1p) (Scavenger mRNA-decapping enzyme DcpS)
Gene: DCS1

Interactor 2: DCPS (Q06151)
m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Hint-related 7meGMP-directed hydrolase 1) (Protein Dcs1p) (Scavenger mRNA-decapping enzyme DcpS)
Gene: DCS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 26258763, 16963086, unassigned1933
Identification Methods x-ray crystallography, molecular sieving, nuclear magnetic resonance, dihydrofolate reductase reconstruction
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DcpS~DcpS, DcpS~DcpS_C, DcpS_C~DcpS_C
Common GO terms GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000340 - RNA 7-methylguanosine cap binding
GO:0000932 - P-body
GO:0000956 - nuclear-transcribed mRNA catabolic process
and 16 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 350
Sc

1 350
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024