Interactor 1: BTK (Q06187)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Gene: BTK
Interactor 2: KPCD1 (Q15139)
Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)
Gene: PRKD1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10561498 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BTK~PH, C1_1~PH, PH~PH, PH~Pkinase, C1_1~PK_Tyr_Ser-Thr, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Pkinase, C1_1~SH2, PH~SH3_1 |
| Common GO terms | GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0035556 - intracellular signal transduction and 5 others more... |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
