Interactor 1: BTK (Q06187)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Gene: BTK
Interactor 2: TLR6 (Q9Y2C9)
Toll-like receptor 6 (CD antigen CD286)
Gene: TLR6
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.43 | 1.00 | 0.656 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12724322 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_8~PK_Tyr_Ser-Thr, LRR_8~SH2 |
| Common GO terms | GO:0002755 - MyD88-dependent toll-like receptor signaling pathway GO:0005886 - plasma membrane GO:0032755 - positive regulation of interleukin-6 production GO:0045087 - innate immune response GO:0045121 - membrane raft and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
