HitPredict

Interactor 1: EXOS9 (Q06265)
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)
Gene: EXOSC9

Interactor 2: C1D (Q13901)
Nuclear nucleic acid-binding protein C1D (hC1D)
Gene: C1D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000176 - nuclear exosome (RNase complex) GO:0000178 - exosome (RNase complex) GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 2 others more... GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 439 Hs			1 141
+	Hs
		1047034 EXOS8_HUMAN (1-275): 1.68e-86: 267: 26.98		C1D_HUMAN (1-141): 2.25e-80: 235: 100.00
+	Hs
		1047019 EXOS7_HUMAN (1-284): 9.95e-83: 257: 26.12		C1D_HUMAN (1-141): 2.25e-80: 235: 100.00
+	Hs
		1047039 EXOS4_HUMAN (14-277): 2.36e-51: 175: 14.76		C1D_HUMAN (1-141): 2.25e-80: 235: 100.00