Interactor 1: EXOS9 (Q06265)
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)
Gene: EXOSC9

Interactor 2: EXOS1 (Q9Y3B2)
Exosome complex component CSL4 (Exosome component 1)
Gene: EXOSC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 26496610, 28514442, 24981860, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ECR1_N~RNase_PH, EXOSC1~RNase_PH, ECR1_N~RNase_PH_C
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 8 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 439
Hs

1 195
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Last updated: 15 Jul 2024